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Found 48 with Last Name = 'sadoun' and Initial = 'f'
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)
Affinity DataKi:  0.400nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of t-PA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443855(CHEMBL3091517)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323009(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-me...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443857(CHEMBL3091501)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323003(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(2...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443858(CHEMBL3091502)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443846(CHEMBL3091527)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443847(CHEMBL3091526)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323007(1-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-met...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443861(CHEMBL3091515)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443844(CHEMBL3091506)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323006(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443848(CHEMBL3091525)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443869(CHEMBL3091507)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443862(CHEMBL3091514)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443867(CHEMBL3091509)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323004(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443865(CHEMBL3091511)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323006(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443864(CHEMBL3091512)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443845(CHEMBL3091528)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443856(CHEMBL3091503)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443866(CHEMBL3091510)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443860(CHEMBL3091505)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50328705(CHEMBL1270156 | Tanogitran)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443863(CHEMBL3091513)
Affinity DataIC50:  3nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443868(CHEMBL3091508)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443859(CHEMBL3091504)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323005(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataIC50:  4.30nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323010(1'-(5-(4-chlorophenyl)-1-(2-cyanoethyl)-4-(2,4-dic...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443849(CHEMBL3091524)
Affinity DataIC50:  13nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM17298(4-[({1-methyl-5-[1-(pyrrolidin-1-ylcarbonyl)cyclop...)
Affinity DataIC50:  15nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323008(1-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-met...)
Affinity DataIC50:  34nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443851(CHEMBL3091521)
Affinity DataIC50:  39nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50129976(4-{4-Methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cy...)
Affinity DataIC50:  84nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443852(CHEMBL3091520)
Affinity DataIC50:  145nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323002(5-(5-(4'-carbamoyl-1,4'-bipiperidine-1'-carbonyl)-...)
Affinity DataIC50:  160nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323001(3-(5-(4'-carbamoyl-1,4'-bipiperidine-1'-carbonyl)-...)
Affinity DataIC50:  180nMAssay Description:Binding affinity to CB1 receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50377608(CHEMBL256941)
Affinity DataIC50:  230nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443850(CHEMBL3091523)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443854(CHEMBL3091518)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50323006(1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...)
Affinity DataEC50:  15nMAssay Description:Antagonist activity at CB1 receptor in forskolin-stimulated human U373-MG cells assessed as inhibition of CP-55940-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed