Compile Data Set for Download or QSAR
maximum 50k data
Found 67 with Last Name = 'savage' and Initial = 'ma'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001092(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  0.900nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001092(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  0.900nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50000335(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  1.80nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001090(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  2.5nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001088((DPDPE)13-[2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  7nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001090(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  9.5nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001093(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  11nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001093(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  11nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  18nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001093(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001093(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001089(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  32nMAssay Description:Dissociation rate constant of compound for mutant T46S Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001089(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  32nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001089(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  45nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001089(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  45nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50000335(13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  58nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001091(10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  91nMAssay Description:Dissociation rate constant of compound for mutant T46A Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001091(10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  91nMAssay Description:Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001091(10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  150nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001091(10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...)
Affinity DataKi:  150nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001088((DPDPE)13-[2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataKi:  700nMAssay Description:Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  2.02E+3nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  0.100nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  0.920nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036806(2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...)
Affinity DataIC50:  3.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  4nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  9.60nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036805(4-(4-{2-Amino-2-[(R)-1-(3-phenyl-propylcarbamoyl)-...)
Affinity DataIC50:  12.3nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036793(2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...)
Affinity DataIC50:  17.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  23.7nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036802((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...)
Affinity DataIC50:  23.7nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036797(2-Amino-3-[4-(4-cyano-benzyloxy)-2,6-dimethyl-phen...)
Affinity DataIC50:  28.6nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50:  32nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453628(CHEMBL2110227)
Affinity DataIC50:  45nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  55nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453629(CHEMBL170594)
Affinity DataIC50:  57nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  64nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036790(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...)
Affinity DataIC50:  124nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50036806(2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...)
Affinity DataIC50:  127nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50453616(CHEMBL2110337)
Affinity DataIC50:  133nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Searle

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  221nMAssay Description:Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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