Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and the value ranges from 3 -5More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and value ranges from 6 - 13More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-HT1A receptor of rat hippocampus and the value ranges from 9 - 12More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-HT1A receptor of rat hippocampus and the value ranges from 9 - 12More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus (94%CI) from 12 to 17More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and the value ranges from 12 to 17.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and the value ranges from 12 to 20.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus. and the value ranges from 16 - 27More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:In vitro ability to inhibit [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and value ranges from 15 - 31More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and value ranges from 27 - 42More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and the value ranges from 25 - 84More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and the value ranges from 48 to 59More data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures.More data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to dopamine receptor D2 of rat limbic structuresMore data for this Ligand-Target Pair
Affinity DataKi: 136nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures and the value ranges from 116 - 159.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 434nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus and the value ranges from 245 to 736More data for this Ligand-Target Pair
Affinity DataKi: 493nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures (95%CI) from 375-661More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus (94%CI) from 391-841More data for this Ligand-Target Pair
Affinity DataKi: 1.03E+3nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures.More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structuresMore data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures.More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structuresMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures.More data for this Ligand-Target Pair
Affinity DataIC50: 38nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of Plasmodium falciparum ENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair