Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Enoyl-ACP reductase' and Ligand = 'BDBM8726'
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 73nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Plasmodium falciparum Enoyl-ACP reductase using crotonyl-CoA as substrate peincubated for 5 mins measured after 10 mins of substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)