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Found 337 with Last Name = 'schow' and Initial = 's'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281406(8-Benzyl-2-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4...)
Affinity DataKi:  1nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281455(3-(2-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  1nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281423(8-Phenethyl-2-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-e...)
Affinity DataKi:  1nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281418(8-Cyclohexylmethyl-3-phenyl-1-oxa-8-aza-spiro[4.5]...)
Affinity DataKi:  1nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281417(8-Cyclohexylmethyl-3-(4-fluoro-phenyl)-1-oxa-8-aza...)
Affinity DataKi:  2nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281438(8-(4-Fluoro-benzyl)-3-phenyl-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  3nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282079((2R,6R)-2,6-Dibenzyl-4-hydroxy-heptanedioic acid b...)
Affinity DataKi:  3.5nMAssay Description:Compound was evaluated for its binding affinity against HIV-1 protease using [125I]-SPA (scintillation proximity assay)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281433(8-Benzyl-3-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281414(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281447(3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281428(8-(4-Fluoro-benzyl)-3-(4-fluoro-phenyl)-1-oxa-8-az...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281459(9-Benzyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2-en...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281453(9-Phenethyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2...)
Affinity DataKi:  5nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281409(2-(4-Fluoro-phenyl)-8-phenethyl-1-oxa-8-aza-spiro[...)
Affinity DataKi:  6nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281450(3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  6nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281452(9-Phenethyl-3-thiophen-2-yl-1-oxa-9-aza-spiro[5.5]...)
Affinity DataKi:  7nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281405(2-(2-Diethylamino-ethyl)-2-methyl-4-phenyl-furan-3...)
Affinity DataKi:  9nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281454(9-Phenethyl-2-phenyl-1-oxa-9-aza-spiro[5.5]undec-2...)
Affinity DataKi:  10nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281435(3-Phenyl-8-(2-thiophen-3-yl-ethyl)-1-oxa-8-aza-spi...)
Affinity DataKi:  12nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281451(8-Benzyl-3-phenyl-1-oxa-8-aza-spiro[5.5]undec-2-en...)
Affinity DataKi:  13nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281413(8-Phenethyl-3-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-e...)
Affinity DataKi:  16nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281408(2-(3-Diethylamino-propyl)-2-methyl-4-phenyl-furan-...)
Affinity DataKi:  16nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281436(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-phenyl-1-oxa...)
Affinity DataKi:  17nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281412(3-(4-Fluoro-phenyl)-8-phenethyl-1-oxa-8-aza-spiro[...)
Affinity DataKi:  24nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281416(2-(4-Methoxy-phenyl)-8-phenethyl-1-oxa-8-aza-spiro...)
Affinity DataKi:  26nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281404(3-(4-Methoxy-phenyl)-8-phenethyl-1-oxa-8-aza-spiro...)
Affinity DataKi:  30nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281457(3-(4-Methoxy-phenyl)-9-phenethyl-1-oxa-9-aza-spiro...)
Affinity DataKi:  30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281434(7-Benzyl-3-phenyl-1-oxa-7-aza-spiro[4.4]non-2-en-4...)
Affinity DataKi:  32nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281444(2-(3-Diethylamino-propyl)-2-methyl-5-phenyl-2,3-di...)
Affinity DataKi:  34nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281440(3-Naphthalen-2-yl-8-phenethyl-1-oxa-8-aza-spiro[4....)
Affinity DataKi:  35nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281443(2-(2-Diethylamino-ethyl)-2-methyl-5-phenyl-furan-3...)
Affinity DataKi:  44nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  47nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281436(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-phenyl-1-oxa...)
Affinity DataKi:  70nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281445(2-Furan-2-yl-9-phenethyl-1-oxa-9-aza-spiro[5.5]und...)
Affinity DataKi:  70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281442(8-Furan-2-ylmethyl-3-phenyl-1-oxa-8-aza-spiro[4.5]...)
Affinity DataKi:  90nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281448(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[5.5...)
Affinity DataKi:  131nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281441(7-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-2-phenyl-1-oxa...)
Affinity DataKi:  152nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281435(3-Phenyl-8-(2-thiophen-3-yl-ethyl)-1-oxa-8-aza-spi...)
Affinity DataKi:  153nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281415(8-Allyl-3-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4-...)
Affinity DataKi:  163nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281424(2,8-Dimethyl-2-phenyl-1-oxa-8-aza-spiro[4.5]decan-...)
Affinity DataKi:  214nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281412(3-(4-Fluoro-phenyl)-8-phenethyl-1-oxa-8-aza-spiro[...)
Affinity DataKi:  217nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281427(2-(2-Dimethylamino-ethyl)-2,4-diphenyl-furan-3-one...)
Affinity DataKi:  223nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281439(8-(3-Chloro-benzyl)-3-phenyl-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  232nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281420(8-Methyl-2-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4...)
Affinity DataKi:  298nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281422(8-methyl-4'-phenyl-3'H-spiro[8-azabicyclo[3.2.1]oc...)
Affinity DataKi:  324nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281458(2-Dimethylaminomethyl-2-methyl-5-phenyl-2,3-dihydr...)
Affinity DataKi:  352nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281441(7-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-2-phenyl-1-oxa...)
Affinity DataKi:  384nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
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