TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.0640nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.0640nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.0730nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]epibatidine from Alpha3 Beta4 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]epibatidine from Alpha3 Beta4 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Eth Zurich (Swiss Federal Institute Of Technology)
Curated by ChEMBL
Eth Zurich (Swiss Federal Institute Of Technology)
Curated by ChEMBL
Affinity DataKi: 0.575nMAssay Description:Binding affinity to human recombinant histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Eth Zurich (Swiss Federal Institute Of Technology)
Curated by ChEMBL
Eth Zurich (Swiss Federal Institute Of Technology)
Curated by ChEMBL
Affinity DataKi: 0.654nMAssay Description:Binding affinity to rat cerebral cortex histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Eth Zurich (Swiss Federal Institute Of Technology)
Curated by ChEMBL
Eth Zurich (Swiss Federal Institute Of Technology)
Curated by ChEMBL
Affinity DataKi: 1.26nMAssay Description:Binding affinity to rat histamine H3 receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 4.01nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.42nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 8.41nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.15nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 20.3nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 21.9nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 26.8nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 44.0nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 46.8nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 49.8nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 54.8nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 56.1nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 73.4nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 74nMAssay Description:Displacement of [3H]epibatidine from Alpha3 Beta4 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 252nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat brain P2 membrane after 45 mins by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 495nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 881nMAssay Description:Displacement of [3H]epibatidine from Alpha3 Beta4 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Swiss Federal Institute Of Technology Zurich
Curated by ChEMBL
Affinity DataKi: 7.91E+3nMAssay Description:Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human full length MMP9 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human full length MMP9 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair