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Found 111 with Last Name = 'schwandner' and Initial = 'r'
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373826(CHEMBL256470)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373827(CHEMBL270865)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373831(CHEMBL272087)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373818(CHEMBL404575)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373815(CHEMBL401756)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373817(CHEMBL404452)
Affinity DataIC50:  260nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373828(CHEMBL427893)
Affinity DataIC50:  310nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305909((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(methylth...)
Affinity DataIC50:  500nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305980((S)-2-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)-3-...)
Affinity DataIC50:  500nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305923((S)-2-(4-chlorophenyl)-4-methyl-N-(thiazol-2-yl)pe...)
Affinity DataIC50:  600nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305906((S)-N-(5-bromothiazol-2-yl)-2-(4-chlorophenyl)-3,3...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305981((S)-2-(4-chlorophenyl)-N-(5-chlorothiazol-2-yl)-3-...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305904((S)-2-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)-3,...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305911((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthi...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373829(CHEMBL429681)
Affinity DataIC50:  730nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373821(CHEMBL401747)
Affinity DataIC50:  730nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305973(2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)butana...)
Affinity DataIC50:  800nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305979((S)-2-(4-chlorophenyl)-3-methyl-N-(5-methylthiazol...)
Affinity DataIC50:  800nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305905((S)-2-(4-chlorophenyl)-N-(5-chlorothiazol-2-yl)-3,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305926((S)-2-(4-chlorophenyl)-N-(thiazol-2-yl)pent-4-enam...)
Affinity DataIC50:  1.10E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305950((S)-2-(4-chlorophenyl)-N-(6-fluoropyridin-2-yl)-3-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305933((S)-2-cyclopropyl-N-(5-fluorothiazol-2-yl)-2-(4-(t...)
Affinity DataIC50:  1.10E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305917((S)-2-(4-chlorophenyl)-N-(5-(1,1,1,3,3,3-hexafluor...)
Affinity DataIC50:  1.20E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305922((S)-2-(4-chlorophenyl)-2-cyclopropyl-N-(5-fluoroth...)
Affinity DataIC50:  1.20E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373814(CHEMBL270877)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305951((S)-2-(4-chlorophenyl)-N-(5-fluoropyridin-2-yl)-3-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305949((S)-2-(4-chlorophenyl)-3-methyl-N-(pyridin-2-yl)bu...)
Affinity DataIC50:  1.40E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305969((S)-2-(4-chlorophenyl)-3-methyl-N-(4-methylthiazol...)
Affinity DataIC50:  1.40E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305930(1-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)cyclobu...)
Affinity DataIC50:  1.50E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305908((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(trifluor...)
Affinity DataIC50:  1.50E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305982((S)-2-(4-chlorophenyl)-3-methyl-N-(5-(trifluoromet...)
Affinity DataIC50:  1.50E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305907((S)-2-(4-chlorophenyl)-N-(5-cyanothiazol-2-yl)-3,3...)
Affinity DataIC50:  1.50E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305913((S)-2-(4-chlorophenyl)-N-(5-(dimethylamino)thiazol...)
Affinity DataIC50:  1.60E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305914((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-morpholin...)
Affinity DataIC50:  1.60E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373819(CHEMBL402218)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at LPA2 assessed as inhibition of LPA-induced Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305978((S)-2-(4-chlorophenyl)-N-(4,5-dimethylthiazol-2-yl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373830(CHEMBL401543)
Affinity DataIC50:  1.86E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305957((S)-2-(4-chlorophenyl)-3-methyl-N-(5-(trifluoromet...)
Affinity DataIC50:  1.90E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305958((S)-2-(4-chlorophenyl)-3-methyl-N-(1,2,4-thiadiazo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305901((S)-2-(4-chlorophenyl)-N-(5-cyanothiazol-2-yl)-3-m...)
Affinity DataIC50:  2.00E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305902((S)-methyl 2-(2-(4-chlorophenyl)-3-methylbutanamid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305964((S)-2-(4-chlorophenyl)-N-(4,5-dihydrothiazol-2-yl)...)
Affinity DataIC50:  2.10E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305954((S)-2-(4-chlorophenyl)-3-methyl-N-(pyridazin-3-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305916((S)-2-(4-Chloro-phenyl)-N-[5-(1,1-dioxo-1lambda*6*...)
Affinity DataIC50:  2.40E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305966(CHEMBL609852 | rac-N-(benzo[d]thiazol-2-yl)-2-(4-c...)
Affinity DataIC50:  3.00E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50373820(CHEMBL270878)
Affinity DataIC50:  3.20E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305910((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(methylsu...)
Affinity DataIC50:  3.40E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305915((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-(4-methyl...)
Affinity DataIC50:  3.80E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305967((S)-N-(5-chlorobenzo[d]oxazol-2-yl)-2-(4-chlorophe...)
Affinity DataIC50:  4.30E+3nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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