Reaction Details Report a problem with these data
Target
Free fatty acid receptor 2
Ligand
BDBM50305926
Substrate
n/a
Meas. Tech.
ChEMBL_605612 (CHEMBL1069216)
IC50
1100±n/a nM
Citation
 Wang, Y; Jiao, X; Kayser, F; Liu, J; Wang, Z; Wanska, M; Greenberg, J; Weiszmann, J; Ge, H; Tian, H; Wong, S; Schwandner, R; Lee, T; Li, Y The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators. Bioorg Med Chem Lett 20:493-8 (2010) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 2
Synonyms:
FFA2 | FFAR2 | FFAR2_HUMAN | G-protein coupled receptor 43 | GPCR43 | GPR43
Type:
PROTEIN
Mol. Mass.:
37156.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508993
Residue:
330
Sequence:
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
  
Inhibitor
Name:
BDBM50305926
Synonyms:
(S)-2-(4-chlorophenyl)-N-(thiazol-2-yl)pent-4-enamide | CHEMBL594738
Type:
Small organic molecule
Emp. Form.:
C14H13ClN2OS
Mol. Mass.:
292.784
SMILES:
Clc1ccc(cc1)[C@H](CC=C)C(=O)Nc1nccs1 |r|
Structure:
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