Affinity DataKi: 0.300nM Kd: 0.100nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Non-competitive inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using varyin...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Non-competitive inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using fixed ...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Non-competitive inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using varyin...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Mixed type inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using fixed N-ter...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 320nM Kd: 71nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 845nM Kd: 167nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMAssay Description:Assay of DOT1L enzymatic activity were performed under balanced conditions using a radiometric assay.More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of full length N-terminal His-tagged SMYD3 (1 to 428 residues) (unknown origin) expressed in Escherichia coli using N-terminal GST-tagged ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human SMYD3 expressed in HEK293T/17 cells using FLAG-tagged MEKK2 as substrate incubated for 30 mins in low air flow area followed by i...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human SMYD3 expressed in HEK293T/17 cells using FLAG-tagged MEKK2 as substrate incubated for 30 mins in low air flow area followed by i...More data for this Ligand-Target Pair