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Found 77 with Last Name = 'shirahashi' and Initial = 'h'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512464(CHEMBL4555442)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512470(CHEMBL4462919)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512464(CHEMBL4555442)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human GST-tagged TRKB (456 to 822) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512463(CHEMBL4528647)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512462(CHEMBL4549659)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512461(CHEMBL4457481)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512471(CHEMBL4457858)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512464(CHEMBL4555442)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512463(CHEMBL4528647)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512473(CHEMBL4591039)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512475(CHEMBL4464600)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512470(CHEMBL4462919)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512460(CHEMBL4555223)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512474(CHEMBL4566514)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512465(CHEMBL4585431)
Affinity DataIC50:  7nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512477(CHEMBL4436442)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512467(CHEMBL4534281)
Affinity DataIC50:  11nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512466(CHEMBL4443955)
Affinity DataIC50:  12nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512461(CHEMBL4457481)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512472(CHEMBL4435536)
Affinity DataIC50:  18nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512473(CHEMBL4591039)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512471(CHEMBL4457858)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512468(CHEMBL4591799)
Affinity DataIC50:  28nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512460(CHEMBL4555223)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512465(CHEMBL4585431)
Affinity DataIC50:  53nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512469(CHEMBL4462390)
Affinity DataIC50:  59nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512477(CHEMBL4436442)
Affinity DataIC50:  64nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512466(CHEMBL4443955)
Affinity DataIC50:  73nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512474(CHEMBL4566514)
Affinity DataIC50:  105nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512467(CHEMBL4534281)
Affinity DataIC50:  127nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512476(CHEMBL4514084)
Affinity DataIC50:  143nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512475(CHEMBL4464600)
Affinity DataIC50:  175nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512462(CHEMBL4549659)
Affinity DataIC50:  224nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512469(CHEMBL4462390)
Affinity DataIC50:  253nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512468(CHEMBL4591799)
Affinity DataIC50:  264nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512472(CHEMBL4435536)
Affinity DataIC50: >300nMAssay Description:Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50512478(CHEMBL4576453)
Affinity DataIC50:  766nMAssay Description:Inhibition of human GST-tagged TRKA (436 to 790) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108088(CHEMBL3601305)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108089(CHEMBL3601306)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108090(CHEMBL3600395)
Affinity DataEC50:  1.55E+3nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108091(CHEMBL3601307)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108092(CHEMBL3601308)
Affinity DataEC50:  812nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108093(CHEMBL3601309)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50029051((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at human alpha1A-adrenergic receptor expressed in HEK293 cells assessed as calcium flux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108094(CHEMBL3601200)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha1B-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108094(CHEMBL3601200)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha1D-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108094(CHEMBL3601200)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha2A-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108094(CHEMBL3601200)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha2B-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108094(CHEMBL3601200)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha2C-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Rattus norvegicus)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50108088(CHEMBL3601305)
Affinity DataEC50:  535nMAssay Description:Agonist activity at rat beta3-adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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