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Found 12 with Last Name = 'shoemark' and Initial = 'dk'
TargetTranscriptional enhancer factor TEF-4(Homo sapiens)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Gal4-fused TEAD2 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-3(Homo sapiens)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Gal4-fused TEAD4 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Gal4-fused TEAD1 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-5(Homo sapiens)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of Gal4-fused TEAD3 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50531837(CHEMBL4578591)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of NL-tagged YAP (unknown origin) interaction with myc-tagged human TEAD1 preincubated for 1 hr followed by NL-tagged YAP addition by Nano...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southmead Hospital

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataIC50:  6.00E+4nMAssay Description:Displacement of [125I]NGF from full length human TrkA expressed in HEKN3S cells cells by gamma counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50531838(Pirazidol | Pirlindole)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to TEAD1 (194 to 411 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southmead Hospital

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataKd:  2.10E+6nMAssay Description:Binding affinity to V305 residue of human recombinant TrkAIg2-NMR construct expressed in Escherichia coli by 1H-15N HSQC NMR spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southmead Hospital

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataKd:  2.10E+6nMAssay Description:Binding affinity to C345 residue of human recombinant TrkAIg2-NMR construct expressed in Escherichia coli by 1H-15N HSQC NMR spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southmead Hospital

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataKd:  2.20E+6nMAssay Description:Binding affinity to F303 residue of human recombinant TrkAIg2-NMR construct expressed in Escherichia coli by 1H-15N HSQC NMR spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southmead Hospital

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataEC50:  8.60E+4nMAssay Description:Antagonist activity at full length glycosylated human TrkA expressed in HEKN3S cells cells assessed as reduction in NGF-induced ERK 42/44 phosphoryla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Southmead Hospital

Curated by ChEMBL
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)
Affinity DataKd:  1.80E+6nMAssay Description:Binding affinity to T292 residue of human recombinant TrkAIg2-NMR construct expressed in Escherichia coli by 1H-15N HSQC NMR spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed