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Found 102 with Last Name = 'silakari' and Initial = 'p'
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094551(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...)
Affinity DataIC50:  0.601nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094542(1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...)
Affinity DataIC50:  0.701nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094539(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126727((S)-4-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-(N-m...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094540(1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094546(3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094534(1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094532(1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094558(3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094548(1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094528(5,6-Dimethyl-1,3-diphenyl-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094535(1,3-diphenyl-4,7-dihydro-2H-isoindole | CHEMBL1408...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094561(3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...)
Affinity DataIC50:  4.51nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094541(1,3-Bis-(4-chloro-phenyl)-4,5,6,7-tetrahydro-2H-is...)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50404086(CHEMBL341226)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126713(CHEMBL282173 | Isoquinoline-5-sulfonic acid 4-{(S)...)
Affinity DataIC50:  5.80nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126702(CHEMBL282807 | Isoquinoline-5-sulfonic acid 4-{(S)...)
Affinity DataIC50:  5.80nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50404085(CHEMBL336619)
Affinity DataIC50:  7.90nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50411888(CHEMBL270421)
Affinity DataIC50:  9.10nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50415889(CHEMBL1098723)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50404090(CHEMBL424451)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126715(CHEMBL27837 | Isoquinoline-5-sulfonic acid 4-[(S)-...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126723((S)-4-(3-(4-(3-chlorophenyl)piperazin-1-yl)-2-(N-m...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094555(5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126718((S)-4-(3-(4-(2-chlorophenyl)piperazin-1-yl)-2-(N-m...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094563(1,3-Di-p-tolyl-4,5,6,7-tetrahydro-2H-isoindole | 1...)
Affinity DataIC50:  16.7nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50423270(CHEMBL393241)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50415882(CHEMBL1094106)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094549(1,3-Bis-(4-methoxy-phenyl)-4,5,6,7-tetrahydro-2H-i...)
Affinity DataIC50:  21.3nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50415908(CHEMBL1094641)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50423276(CHEMBL396587)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126712(CHEMBL27711 | Isoquinoline-5-sulfonic acid 4-{(S)-...)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094550(3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...)
Affinity DataIC50:  35.6nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50410952(CHEMBL208560)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094537(1-(4-(1H-imidazol-1-yl)phenyl)-3-(4-fluorophenyl)-...)
Affinity DataIC50:  42.1nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50423280(CHEMBL245561)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50415888(CHEMBL1096314)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50423272(CHEMBL246578)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50415891(CHEMBL1094744)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50495434(CHEMBL131241)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126719((S)-4-(3-(4-benzylpiperazin-1-yl)-2-(N-methylisoqu...)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126724(CHEMBL282808 | Isoquinoline-5-sulfonic acid 4-{(S)...)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50411878(CHEMBL245754)
Affinity DataIC50:  78nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50415909(CHEMBL1094482)
Affinity DataIC50:  79nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  94nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126717(CHEMBL286496 | Isoquinoline-5-sulfonic acid 4-{(S)...)
Affinity DataIC50:  98nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094560(CHEMBL337601 | N-{5-[5-(3-Acetylamino-4-fluoro-phe...)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094544((1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-yl)-ac...)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094553(1,3-Bis-(4-imidazol-1-yl-phenyl)-4,5,6,7-tetrahydr...)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Dr Hs Gour University

Curated by ChEMBL
LigandPNGBDBM50094531(1N-methyl-2-fluoro-5-[5-(4-fluoro-3-methylaminophe...)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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