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Found 3 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50126723'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50126723((S)-4-(3-(4-(3-chlorophenyl)piperazin-1-yl)-2-(N-m...)
Affinity DataIC50:  12.6nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50126723((S)-4-(3-(4-(3-chlorophenyl)piperazin-1-yl)-2-(N-m...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at P2X7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50126723((S)-4-(3-(4-(3-chlorophenyl)piperazin-1-yl)-2-(N-m...)
Affinity DataIC50:  14nMAssay Description:Antagonistic activity against P2X7 receptor measured as the ATP dependent calcium influx in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed