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Found 210 with Last Name = 'silva' and Initial = 'am'
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50445691(CHEMBL243677)
Affinity DataKi:  1.80E+4nMAssay Description:Uncompetitive inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Affinity DataKi:  1.94E+4nMAssay Description:Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataKi:  8.45E+4nMAssay Description:Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50445690(CHEMBL457821)
Affinity DataKi:  9.54E+4nMAssay Description:Uncompetitive inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50312650(5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...)
Affinity DataKi:  1.03E+5nMAssay Description:Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataKi:  1.07E+5nMAssay Description:Uncompetitive inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  1.22E+5nMAssay Description:Uncompetitive inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  1.78E+5nMAssay Description:Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50:  0.0680nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587754(CHEMBL5197518)
Affinity DataIC50:  0.0920nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610559(CHEMBL5286535)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50587754(CHEMBL5197518)
Affinity DataIC50:  0.211nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610557(CHEMBL5272625)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50587753(CHEMBL5190569)
Affinity DataIC50:  0.255nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610558(CHEMBL5269238)
Affinity DataIC50:  0.284nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610556(CHEMBL5266033)
Affinity DataIC50:  0.334nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610558(CHEMBL5269238)
Affinity DataIC50:  0.479nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610559(CHEMBL5286535)
Affinity DataIC50:  0.624nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610556(CHEMBL5266033)
Affinity DataIC50:  0.628nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610557(CHEMBL5272625)
Affinity DataIC50:  0.864nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610554(CHEMBL5289994)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610555(CHEMBL5267312)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610549(CHEMBL5276338)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610553(CHEMBL5277927)
Affinity DataIC50:  3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610564(CHEMBL5282833)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610565(CHEMBL5274465)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50217942(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610547(CHEMBL5268897)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610546(CHEMBL1613299)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610552(CHEMBL5273978)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50276368(CHEMBL4128371)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610561(CHEMBL5291052)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610549(CHEMBL5276338)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610551(CHEMBL5279409)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50241867(((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hy...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610547(CHEMBL5268897)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM31895(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 20....)
Affinity DataIC50:  7nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610566(CHEMBL5278429)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610545(CHEMBL5266286)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610562(CHEMBL5275941)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610544(CHEMBL5268019)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM31900(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 25....)
Affinity DataIC50:  11nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610563(CHEMBL5272974)
Affinity DataIC50:  11nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM31901(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 26....)
Affinity DataIC50:  11nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610561(CHEMBL5291052)
Affinity DataIC50:  11nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610560(CHEMBL5265752)
Affinity DataIC50:  12nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50610550(CHEMBL5290959)
Affinity DataIC50:  13nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM31902(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 27....)
Affinity DataIC50:  14nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50610560(CHEMBL5265752)
Affinity DataIC50:  14nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50404156(CHEMBL5272243)
Affinity DataIC50:  16nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
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