Found 26 with Last Name = 'simizu' and Initial = 's' 
Affinity DataIC50: 48nM Kd: 29nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 72nM Kd: 100nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 137nM Kd: 208nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 156nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 203nM Kd: 435nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 299nM Kd: 426nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 453nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 565nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 627nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 693nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 958nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.53E+3nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.85E+3nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+3nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Riken Discovery Research Institute
Curated by ChEMBL
Riken Discovery Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human HeLa cell adhesion to fibronectinMore data for this Ligand-Target Pair
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Riken Discovery Research Institute
Curated by ChEMBL
Riken Discovery Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human A431 cell adhesion to fibronectinMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:Reductase activity was assayed by measuring the PDI-catalyzed reduction of insulin in the presence of DTT, thus measuring the aggregation of reduced ...More data for this Ligand-Target Pair
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Riken Discovery Research Institute
Curated by ChEMBL
Riken Discovery Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human HT-1080 cell adhesion to fibronectinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for inhibitory activity against heparanaseMore data for this Ligand-Target Pair
