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TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97666(US8476295, 1.1.04)
Affinity DataKi:  10nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97664(US8476295, 1.1.02)
Affinity DataKi:  20nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97665(US8476295, 1.1.03)
Affinity DataKi:  21nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97663(US8476295, 1.1.01)
Affinity DataKi:  29nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97666(US8476295, 1.1.04)
Affinity DataKi:  35nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97665(US8476295, 1.1.03)
Affinity DataKi:  59nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97663(US8476295, 1.1.01)
Affinity DataKi:  72nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97664(US8476295, 1.1.02)
Affinity DataKi:  91nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97667(US8476295, 2.1.01)
Affinity DataKi:  220nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [11-552](Homo sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97668(US8476295, 3.1.01)
Affinity DataKi:  464nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97667(US8476295, 2.1.01)
Affinity DataKi:  806nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1 [17-535](Homo Sapiens (Human))
Inspire

US Patent
LigandPNGBDBM97668(US8476295, 3.1.01)
Affinity DataKi:  976nMpH: 7.2Assay Description:Inhibition of Rho kinase 2 and Rho kinase I activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021135(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405179(CHEMBL2114418)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021133(2-(5-Carboxymethyl-1,4-dioxo-2,3,4,5-tetrahydro-1H...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021134(2-(5-Carboxymethyl-4-oxo-2,3,4,5-tetrahydro-benzo[...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107901(US8604218, 1.052)
Affinity DataIC50:  15.3nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107948(US8604218, 1.099)
Affinity DataIC50:  25.8nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107938(US8604218, 1.089)
Affinity DataIC50:  29.4nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108011(US8604218, 2.025)
Affinity DataIC50:  29.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107930(US8604218, 1.081)
Affinity DataIC50:  30.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107931(US8604218, 1.082)
Affinity DataIC50:  30.4nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107908(US8604218, 1.059)
Affinity DataIC50:  32nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107951(US8604218, 1.102)
Affinity DataIC50:  34.3nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107949(US8604218, 1.100)
Affinity DataIC50:  42.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107907(US8604218, 1.058)
Affinity DataIC50:  47.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107940(US8604218, 1.091)
Affinity DataIC50:  49.4nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107926(US8604218, 1.077)
Affinity DataIC50:  53.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107896(US8604218, 1.047)
Affinity DataIC50:  57nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107921(US8604218, 1.072)
Affinity DataIC50:  58.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107973(US8604218, 1.124)
Affinity DataIC50:  59.2nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107900(US8604218, 1.051)
Affinity DataIC50:  62.6nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107927(US8604218, 1.078)
Affinity DataIC50:  63.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107857(US8604218, 1.008)
Affinity DataIC50:  65.8nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107950(US8604218, 1.101)
Affinity DataIC50:  68.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107883(US8604218, 1.034)
Affinity DataIC50:  69.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107955(US8604218, 1.106)
Affinity DataIC50:  69.2nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107886(US8604218, 1.037)
Affinity DataIC50:  69.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107923(US8604218, 1.074)
Affinity DataIC50:  71.6nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107992(US8604218, 2.006)
Affinity DataIC50:  73.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107924(US8604218, 1.075)
Affinity DataIC50:  74.5nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107882(US8604218, 1.033)
Affinity DataIC50:  86.9nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108017(US8604218, 2.031)
Affinity DataIC50:  87.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107909(US8604218, 1.060)
Affinity DataIC50:  87.2nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107987(US8604218, 2.001)
Affinity DataIC50:  98.8nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108025(US8604218, 2.039)
Affinity DataIC50:  101nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107942(US8604218, 1.093)
Affinity DataIC50:  101nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107928(US8604218, 1.079)
Affinity DataIC50:  102nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent
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