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Found 102 with Last Name = 'slater' and Initial = 'mj'
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081842(2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against HCMV protease by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081846(2-(1-Acetyl-2-oxo-propyl)-3-chloro-[1,4]naphthoqui...)
Affinity DataIC50:  720nMAssay Description:Inhibitory activity against HCMV protease by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081842(2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against HCMV protease by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081846(2-(1-Acetyl-2-oxo-propyl)-3-chloro-[1,4]naphthoqui...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against HCMV protease by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50503730(CHEMBL4443278)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081843(2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibitory activity against HCMV protease by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071777(5-bromo-2-({6-[(4-bromo-2-carboxyphenyl)amino]-6-o...)
Affinity DataIC50:  1.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071776(2-({6-[(2-carboxy-4-chlorophenyl)amino]-6-oxohexan...)
Affinity DataIC50:  1.80E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081845(2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibitory activity against HCMV protease by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071777(5-bromo-2-({6-[(4-bromo-2-carboxyphenyl)amino]-6-o...)
Affinity DataIC50:  3.10E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071766(5-bromo-2-[5-(4-bromo-2-carboxyphenylcarbamoyl)pen...)
Affinity DataIC50:  3.80E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM24774(2,3-dichloro-1,4-dihydronaphthalene-1,4-dione | 2,...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory activity against HCMV protease by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071768(2-({6-[(2-carboxy-4-iodophenyl)amino]-6-oxohexanoy...)
Affinity DataIC50:  4.10E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071765(2-[4-(2-carboxy-4-methoxyphenylcarbamoyl)butylcarb...)
Affinity DataIC50:  4.30E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071766(5-bromo-2-[5-(4-bromo-2-carboxyphenylcarbamoyl)pen...)
Affinity DataIC50:  4.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081843(2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against HCMV protease by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM24774(2,3-dichloro-1,4-dihydronaphthalene-1,4-dione | 2,...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against HCMV protease by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071771(5-bromo-2-{[(5-{[(4-bromo-2-carboxyphenyl)amino]ca...)
Affinity DataIC50:  5.50E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50248131(CHEMBL3754093)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071767(2-({6-[(2-carboxy-4-hydroxyphenyl)amino]-6-oxohexa...)
Affinity DataIC50:  6.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071779(2-[4-(2-carboxy-4-methylsulfanylphenylcarbamoyl)bu...)
Affinity DataIC50:  6.90E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071762(5-bromo-2-({5-[(4-bromo-2-carboxyphenyl)amino]-5-o...)
Affinity DataIC50:  7.30E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071761(5-bromo-2-[6-(4-bromo-2-carboxyphenylcarbamoyl)hex...)
Affinity DataIC50:  7.40E+3nMAssay Description:Compound was evaluated for inhibition of HIV-2 reverse transcriptase using rC.dG and [3H]-dGTP as substrates at 100 microg/mlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071778(2-[4-(2-carboxy-4-trifluoromethylphenylcarbamoyl)b...)
Affinity DataIC50:  8.30E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071768(2-({6-[(2-carboxy-4-iodophenyl)amino]-6-oxohexanoy...)
Affinity DataIC50:  8.50E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071776(2-({6-[(2-carboxy-4-chlorophenyl)amino]-6-oxohexan...)
Affinity DataIC50:  8.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071774(2-({5-[(2-carboxy-4-chlorophenyl)amino]-5-oxopenta...)
Affinity DataIC50:  8.70E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071763(2-({6-[(2-carboxyphenyl)amino]-6-oxohexanoyl}amino...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071773(2-[5-(2-carboxy-4-chlorophenylcarbamoyl)pentylcarb...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071773(2-[5-(2-carboxy-4-chlorophenylcarbamoyl)pentylcarb...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071763(2-({6-[(2-carboxyphenyl)amino]-6-oxohexanoyl}amino...)
Affinity DataIC50:  9.00E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081845(2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibitory activity against HCMV protease by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071770(2-[4-(2-carboxy-4-methylphenylcarbamoyl)butylcarbo...)
Affinity DataIC50:  9.20E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071774(2-({5-[(2-carboxy-4-chlorophenyl)amino]-5-oxopenta...)
Affinity DataIC50:  9.60E+3nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071762(5-bromo-2-({5-[(4-bromo-2-carboxyphenyl)amino]-5-o...)
Affinity DataIC50:  1.00E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071765(2-[4-(2-carboxy-4-methoxyphenylcarbamoyl)butylcarb...)
Affinity DataIC50:  1.06E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071778(2-[4-(2-carboxy-4-trifluoromethylphenylcarbamoyl)b...)
Affinity DataIC50:  1.20E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50081847(2-Chloro-3-(3-cyclohexyl-propyl)-[1,4]naphthoquino...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibitory activity against HCMV protease by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071780(5-bromo-2-[(3-{[(4-bromo-2-carboxyphenyl)amino]car...)
Affinity DataIC50:  1.40E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071770(2-[4-(2-carboxy-4-methylphenylcarbamoyl)butylcarbo...)
Affinity DataIC50:  1.40E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071764(5-Bromo-2-[5-(4-bromo-phenylcarbamoyl)-pentanoylam...)
Affinity DataIC50:  1.50E+4nMAssay Description:Evaluated for inhibition of HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071760(5-bromo-2-{[(3-{[(4-bromo-2-carboxyphenyl)amino]ca...)
Affinity DataIC50:  1.50E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50503727(CHEMBL4560686)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071761(5-bromo-2-[6-(4-bromo-2-carboxyphenylcarbamoyl)hex...)
Affinity DataIC50:  1.80E+4nMAssay Description:Compound was evaluated for inhibition of HIV-1 reverse transcriptase using rC.dG and [3H]-dGTP as substrates at 100 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071780(5-bromo-2-[(3-{[(4-bromo-2-carboxyphenyl)amino]car...)
Affinity DataIC50:  1.90E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Glaxowellcome Medicines Research Center

Curated by ChEMBL
LigandPNGBDBM50071779(2-[4-(2-carboxy-4-methylsulfanylphenylcarbamoyl)bu...)
Affinity DataIC50:  1.90E+4nMAssay Description:Evaluated for inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50503726(CHEMBL4483318)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein Rev(Human immunodeficiency virus 1)
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50503720(CHEMBL4583631)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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