Affinity DataKi: 0.0140nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.160nM Kon: 4.90M-1s-1 Koff: 3.05E+4s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nM Kon: 0.00000207M-1s-1 Koff: 6.63E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Center For Neurologic Study
US Patent
Center For Neurologic Study
US Patent
Affinity DataKi: 1.60nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.70nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 1.73nM Kon: 0.0000109M-1s-1 Koff: 6.31E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibitory activity of the compound against Cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Center For Neurologic Study
US Patent
Center For Neurologic Study
US Patent
Affinity DataKi: 7.80nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Center For Neurologic Study
US Patent
Center For Neurologic Study
US Patent
Affinity DataKi: 15.3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 17nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Center For Neurologic Study
US Patent
Center For Neurologic Study
US Patent
Affinity DataKi: 20nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 20nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Center For Neurologic Study
US Patent
Center For Neurologic Study
US Patent
Affinity DataKi: 20.5nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Center For Neurologic Study
US Patent
Center For Neurologic Study
US Patent
Affinity DataKi: 22nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 22nMAssay Description:Displacement of [3H]CP559440 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair