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Found 85 with Last Name = 'soga' and Initial = 't'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069631(CHEMBL3402520)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069632(CHEMBL3402521)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069628(CHEMBL3402517)
Affinity DataIC50:  7.60nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069627(CHEMBL3402516)
Affinity DataIC50:  9.5nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069630(CHEMBL3402519)
Affinity DataIC50:  11nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069625(CHEMBL2398246)
Affinity DataIC50:  15nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069629(CHEMBL3402518)
Affinity DataIC50:  15nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50069626(CHEMBL3402515)
Affinity DataIC50:  21nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with His-tagged p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392531(CHEMBL407632)
Affinity DataIC50:  140nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392546(CHEMBL2152330)
Affinity DataIC50:  140nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50489368(CHEMBL2315846)
Affinity DataIC50:  140nMAssay Description:Inhibition of human His-tagged p53 (1 to 132 amino acid residues)/GST-tagged MDM2 L33E mutant (25 to 108 amino acid residues) interaction by HTRF ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480036(CHEMBL459363)
Affinity DataIC50:  151nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392535(CHEMBL2152320)
Affinity DataIC50:  160nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392535(CHEMBL2152320)
Affinity DataIC50:  160nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480040(CHEMBL475295)
Affinity DataIC50:  165nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataIC50:  180nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392535(CHEMBL2152320)
Affinity DataIC50:  260nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392542(CHEMBL2152326)
Affinity DataIC50:  340nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480026(CHEMBL514342)
Affinity DataIC50:  379nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480037(CHEMBL459364)
Affinity DataIC50:  414nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480015(CHEMBL518023)
Affinity DataIC50:  705nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480030(CHEMBL512390)
Affinity DataIC50:  807nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392540(CHEMBL2152324)
Affinity DataIC50:  840nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480016(CHEMBL459365)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480030(CHEMBL512390)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392543(CHEMBL2152327)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480040(CHEMBL475295)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392545(CHEMBL2152329)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480032(CHEMBL460017)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480031(CHEMBL460641)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480035(CHEMBL460401)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480033(CHEMBL461685)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480014(CHEMBL450370)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480026(CHEMBL514342)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480033(CHEMBL461685)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392544(CHEMBL2152328)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392534(CHEMBL2152319)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480038(CHEMBL460640)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480032(CHEMBL460017)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480038(CHEMBL460640)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480017(CHEMBL470439)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480034(CHEMBL511357)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392533(CHEMBL2152318)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480039(CHEMBL461684)
Affinity DataIC50:  2.89E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480024(CHEMBL512389)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of CDK4-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480031(CHEMBL460641)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392538(CHEMBL2152323)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392536(CHEMBL2152321)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50480036(CHEMBL459363)
Affinity DataIC50:  3.79E+3nMAssay Description:Inhibition of CDK2-mediated retinoblastoma protein phosphorylation by dose-response curve analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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