TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital
Curated by ChEMBL
Seoul National University Bundang Hospital
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Pohang University of Science and Technology
Curated by PDSP Ki Database
Pohang University of Science and Technology
Curated by PDSP Ki Database
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.710nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:As such, the compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profili...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Src kinase (unknown origin)More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Konkuk University
Curated by ChEMBL
Konkuk University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:As such, the compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profili...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
Affinity DataIC50: 2.12nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.37nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.49nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair