TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Competitive inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by Lineweaver-Burk plot analysis in presence of...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Time dependent inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate measured every 30 secs by Morrison and Walsh...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 to 60 mins by Lineweaver-Bur...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Competitive inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 to 60 mins by Lineweaver-Burk and ...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 151nMAssay Description:Time dependent inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate measured every 30 secs by Morrison and Walsh...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 499nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate incubated for 10 mins measured for 30...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.21E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.49E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.75E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate incubated for 10 mins measured for 30...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 to 60 mins by Lineweaver-Bur...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Time dependent inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate preincubated with enz...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Non-competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 4.38E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 60 mins followed by ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Non-competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 5.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.60E+3nMAssay Description:Mixed type inhibition of alpha-glucosidase (unknown origin) assessed as enzyme-substrate-inhibitor complex formation using PNP-G as substrate by Line...More data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 7.50E+3nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 to 60 mins by Lineweaver-Bur...More data for this Ligand-Target Pair
Affinity DataKi: 8.20E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 8.90E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 9.60E+3nMAssay Description:Non-competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 9.90E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.11E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.23E+4nMAssay Description:Competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.34E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.76E+4nMAssay Description:Competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.77E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.92E+4nMAssay Description:Non-competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.92E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 1.99E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.29E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.72E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.93E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.95E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 2.99E+4nMAssay Description:Non-competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Gyeongsang National University
Curated by ChEMBL
Gyeongsang National University
Curated by ChEMBL
Affinity DataKi: 3.27E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.39E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysisMore data for this Ligand-Target Pair