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Found 5 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50134710'
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50134710(CHEMBL3745886)
Affinity DataKi:  151nMAssay Description:Time dependent inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate measured every 30 secs by Morrison and Walsh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50134710(CHEMBL3745886)
Affinity DataKi:  1.80E+3nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 to 60 mins by Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50134710(CHEMBL3745886)
Affinity DataKi:  7.64E+4nMAssay Description:Competitive inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 to 60 mins by Lineweaver-Burk and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50134710(CHEMBL3745886)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated with substrate for 10 mins followed by protein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50134710(CHEMBL3745886)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed