Found 141 with Last Name = 'soriano' and Initial = 'c' 
Affinity DataKi: 200nMAssay Description:Mixed non-competitive inhibition of Leishmania infantum TryR using TS2 as substrate assessed as inhibition constant of two-step induced-fit mechanism...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 6.2 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 12.5 uM TS2 by DTNB-reagent based ...More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 3.1 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 25 uM TS2 by DTNB-reagent based sp...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Mixed non-competitive inhibition of Leishmania infantum TryR using TS2 as substrate assessed as inhibition constant of first equilibrium by plot anal...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 100 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 50 uM TS2 by DTNB-reagent based sp...More data for this Ligand-Target Pair
Affinity DataKi: 2.83E+3nMAssay Description:Non competitive type inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 100 uM TS2 by DTNB-...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 12.5 uM TS2 by DTNB...More data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 6.2 uM TS2 by DTNB-...More data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Competitive inhibition of HIS-FLAG-tagged recombinant Leishmania infantum TryR expressed in Escherichia coli using TS2 substrate assessed as inhibiti...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 25 uM TS2 by DTNB-r...More data for this Ligand-Target Pair
Affinity DataKi: 8.90E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 3.1 uM TS2 by DTNB-...More data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 50 uM TS2 by DTNB-r...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma brucei TryR oxidoreductase activity using TS2 as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of HIS-tagged recombinant Trypanosoma congolense TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by sp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HIS-tagged recombinant Trypanosoma congolense TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by sp...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of HIS-tagged recombinant Trypanosoma brucei TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spectr...More data for this Ligand-Target Pair
Ligand Info
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of HIS-tagged recombinant Trypanosoma brucei TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spectr...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Trypanosoma brucei TryR oxidoreductase activity using TS2 as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of HIS-tagged recombinant Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli in the presence of NADPH by spect...More data for this Ligand-Target Pair
Ligand Info
