Found 15 Enz. Inhib. hit(s) with Target = 'Trypanothione reductase' and Ligand = 'BDBM50571699' TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 12.5 uM TS2 by DTNB-reagent based ...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 6.2 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 3.1 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 25 uM TS2 by DTNB-reagent based sp...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 100 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 50 uM TS2 by DTNB-reagent based sp...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 100 uM TS2 by DTNB-...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 5.20E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 12.5 uM TS2 by DTNB...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 6.2 uM TS2 by DTNB-...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 25 uM TS2 by DTNB-r...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 8.90E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 3.1 uM TS2 by DTNB-...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 9.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 50 uM TS2 by DTNB-r...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL2(DE3) using TS2 as substrate b...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Leishmania infantum)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant His-FLAG-tagged Leishmania infantum TryR dimerization expressed in Escherichia coli BL2(DE3) assessed as reduction in TryR ...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Trypanosoma brucei TryR oxidoreductase activity using TS2 as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
