TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-LY459477 from human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 166nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Mixed non-competitive inhibition of Leishmania infantum TryR using TS2 as substrate assessed as inhibition constant of two-step induced-fit mechanism...More data for this Ligand-Target Pair
Ligand Info
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 238nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 251nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 268nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 271nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 369nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 12.5 uM TS2 by DTNB-reagent based ...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 6.2 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 3.1 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 614nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 728nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 25 uM TS2 by DTNB-reagent based sp...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Mixed non-competitive inhibition of Leishmania infantum TryR using TS2 as substrate assessed as inhibition constant of first equilibrium by plot anal...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 100 uM TS2 by DTNB-reagent based s...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as overall apparent inhibition constant in presence of 50 uM TS2 by DTNB-reagent based sp...More data for this Ligand-Target Pair
Affinity DataKi: 2.83E+3nMAssay Description:Non competitive type inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of recombinant Leishmania infantum TryR assessed as apparent inhibition constant for initial EI complex in presence of 100 uM TS2 by DTNB-...More data for this Ligand-Target Pair