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Found 38 with Last Name = 'spellmeyer' and Initial = 'dc'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.320nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.540nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  1.40nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  4nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50039664(CHEMBL91890 | N-Biphenyl-4-yl-N-[(carbamoylmethyl-...)
Affinity DataKi:  4nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM50472725(CHEMBL90588 | CHIR-2279)
Affinity DataKi:  5nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50039665(CHEMBL90649 | CHIR-4531 | N-Benzo[1,3]dioxol-5-ylm...)
Affinity DataKi:  6nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from rat brain membrane using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50039661(CHEMBL327549 | CHIR-4537 | N-({Carbamoylmethyl-[2-...)
Affinity DataKi:  31nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from rat brain membrane using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50039663(CHEMBL89378 | CHIR-4534 | N-({Carbamoylmethyl-[2-(...)
Affinity DataKi:  46nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from rat brain membrane using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM50472726(CHEMBL92380 | CHIR-2283)
Affinity DataKi:  140nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Combichem

Curated by ChEMBL
LigandPNGBDBM50472727(CHEMBL92379 | CHIR-2276)
Affinity DataKi:  310nMAssay Description:Evaluated for binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Affinity DataKi:  4.00E+3nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron

Curated by ChEMBL
LigandPNGBDBM50029051((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Affinity DataKi:  1.40E+4nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281579((S)-3-{2-[((R)-2-Acetylamino-3-phenyl-propionyl)-b...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50:  15nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281577((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281579((S)-3-{2-[((R)-2-Acetylamino-3-phenyl-propionyl)-b...)
Affinity DataIC50:  30nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50:  45nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281580((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  57nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281581((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  70nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281582((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  75nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281575((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281585((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  79nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281587((S)-3-[(R)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  98nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281583((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  114nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50:  130nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptor in rabbit renal artery tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281910((S)-3-[(S)-5-((S)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  230nMAssay Description:Binding affinity of the compound for Endothelin A receptor was determined in murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281584((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  230nMAssay Description:The compound was tested for the binding affinity against eEndothelin A receptor in murine 3T3 cells using [125I]-ET-1 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281911((R)-3-[(R)-5-((S)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  250nMAssay Description:Binding affinity of the compound for Endothelin A receptor was determined in murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281578((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  270nMAssay Description:Inhibition of [125I]-ET-1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281577((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  400nMAssay Description:The inhibitory constant of the compound was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281584((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: <800nMAssay Description:The inhibitory constant was evaluated against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281912((S)-3-[(R)-5-((S)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50:  900nMAssay Description:Binding affinity of the compound for Endothelin A receptor was determined in murine 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article