Compile Data Set for Download or QSAR
maximum 50k data
Found 21 with Last Name = 'spitzer' and Initial = 'd'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  2.62nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351992(CHEMBL1822599)
Affinity DataKi:  9.08nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464785(CHEMBL4292641)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351993(CHEMBL1822600)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464784(CHEMBL4290541)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464783(CHEMBL4285825)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464789(CHEMBL4284762)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351990(CHEMBL1822597)
Affinity DataKi:  78.7nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351991(CHEMBL1822598)
Affinity DataKi:  96.2nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351988(CHEMBL1822595)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351989(CHEMBL1822596)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464786(CHEMBL4277892)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464787(CHEMBL4293027)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464788(CHEMBL4282423)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464783(CHEMBL4285825)
Affinity DataEC50:  2.83E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464784(CHEMBL4290541)
Affinity DataEC50:  3.04E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464785(CHEMBL4292641)
Affinity DataEC50:  7.64E+4nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353845(CHEMBL1830149 | US9604926, Compound CM-341 | US972...)
Affinity DataEC50:  460nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353847(CHEMBL1831157 | US9604926, Compound CM-360 | US972...)
Affinity DataEC50:  6.09E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464787(CHEMBL4293027)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed