Affinity DataIC50: 2.38nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Redx Pharma
Curated by ChEMBL
Redx Pharma
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 9.93nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Redx Pharma
Curated by ChEMBL
Redx Pharma
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 11.3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15.5nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19.9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Redx Pharma
Curated by ChEMBL
Redx Pharma
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 22.6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23.2nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23.8nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Redx Pharma
Curated by ChEMBL
Redx Pharma
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 37.3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38.6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Redx Pharma
Curated by ChEMBL
Redx Pharma
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 79.4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Redx Pharma
Curated by ChEMBL
Redx Pharma
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 as substrate incubated for 30 mins by ethidium bromide staining based gel electro...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV using kDNA as substrate incubated for 30 mins by ethidium bromide staining based gel electrophor...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Redx Anti-Infectives
Curated by ChEMBL
Redx Anti-Infectives
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair