Found 208 with Last Name = 'sundermann' and Initial = 'b' 
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal
US Patent
Gruenenthal
US Patent
Affinity DataKi: 0.100nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nM ΔG°: -54.7kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -54.4kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal
US Patent
Gruenenthal
US Patent
Affinity DataKi: 0.300nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nM ΔG°: -53.9kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -53.1kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -53.1kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.6kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.6kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.6kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -52.3kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal
US Patent
Gruenenthal
US Patent
Affinity DataKi: 0.700nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.6kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal
US Patent
Gruenenthal
US Patent
Affinity DataKi: 0.900nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -51.1kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Gruenenthal
US Patent
Gruenenthal
US Patent
Affinity DataKi: 1.10nMAssay Description:The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -50.9kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -50.9kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -50.9kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -50.7kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nM ΔG°: -50.4kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -50.2kJ/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nM ΔG°: -50.1kJ/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 minsMore data for this Ligand-Target Pair
