Affinity DataKi: 0.630nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is in between (0.62-0.65)More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is between (0.66-0.95)More data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is between (0.35-2.5)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membrane;Range is in between (1.8-2.2)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is between (1.7-2.3)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is between (1-3.9)More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membrane;Range is in between (1.3-3.7)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membrane;Range is in between (6.8-43)More data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -39.1kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membrane;Range is in between (110-150)More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor delta 1 expressed in CHO cell membrane;Range is between (63-360)More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -37.3kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor kappa 1 expressed in CHO cell membrane;Range is in between (1400-1900)More data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membrane;Range is in between (580-680)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor kappa 1 expressed in CHO cell membrane;Range is in between (1400-1900)More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nM ΔG°: -33.5kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor kappa 1 expressed in CHO cell membrane;Range is in between (1400-1900)More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nM ΔG°: -31.4kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nM ΔG°: -30.9kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nM ΔG°: -30.0kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Inhibition of binding of [3H]-diprenorphine to cloned human Opioid receptor kappa 1 expressed in CHO cell membrane; range is in between (4700-8500)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor kappa 1 expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor kappa 1 expressed in CHO cell membrane;Range is in between (1400-1900)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [3H]diprenorphine to cloned human Opioid receptor mu 1 expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nM ΔG°: -27.8kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nM ΔG°: -25.6kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deference (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deferens (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deferens (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deference (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deference (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 307nMAssay Description:Inhibition of VHL (unknown origin) assessed as phosphorylated peptide substrate incubated for 60 mins by TR-FRET based biochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 644nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of mouse vas deference (MVD, delta receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human GST-tagged ERK5 (1 to 398 assessed as phosphorylated peptide substrate incubated for 60 mins by TR-FRET based biochem...More data for this Ligand-Target Pair
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of NanoLuc-tagged VHL in HEK293 cells incubated for 2 hrs by NanoBRET live cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Ability to inhibit electrically evoked contractions of isolated muscle preparations of guinea pig ileum (GPI, mu receptor)More data for this Ligand-Target Pair