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TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250921(CHEMBL518103 | isaindigotone)
Affinity DataIC50:  40nMAssay Description:Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250946(3-(4'-Acetoxy-3',5'-dimethoxy)benzylidene-1,2-dihy...)
Affinity DataIC50:  60nMAssay Description:Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250926(1-ethyl-6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyr...)
Affinity DataIC50:  90nMAssay Description:Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of bee venom group3 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of bee venom group3 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic phospholipase A2 2(Indian cobra)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Naja naja venom group1 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of bee venom group3 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rat)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of rat air pouch group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic phospholipase A2 2(Indian cobra)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of Naja naja venom group1 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rat)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rat)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  3.69E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rat)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  3.84E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  6.25E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rat)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  6.51E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  8.67E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  9.07E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  9.32E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  9.48E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Honeybee)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  9.48E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Human)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  9.67E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed