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Found 42 with Last Name = 'thompson' and Initial = 'md'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014354(6-[4,4-Bis-(4-fluoro-phenyl)-3-(1-methyl-1H-tetraz...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014356(CHEMBL320666 | Sodium; 9,9-bis-(4-fluoro-2-methyl-...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50:  43nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014358(CHEMBL103192 | Sodium; 9-(4-fluoro-phenyl)-3,5-dih...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014355(CHEMBL103585 | Sodium; 7-(4'-fluoro-3,5,3'-trimeth...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014365(CHEMBL103547 | Sodium; 9,9-bis-(4-fluoro-3-methyl-...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014361(CHEMBL318754 | Sodium; 3,5-dihydroxy-8-(1-methyl-1...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014364(CHEMBL318102 | Sodium; 8-[bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014363(CHEMBL419542 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014349(CHEMBL328846 | Sodium; 9,9-bis-(2-fluoro-4-methyl-...)
Affinity DataIC50:  580nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014362(CHEMBL103661 | Sodium; 8-(1-ethyl-1H-tetrazol-5-yl...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014346(CHEMBL441642 | Sodium; 3,5-dihydroxy-8-(1-methyl-1...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227555(US9340511, 4 | US9708269, 4f)
Affinity DataIC50:  1.40E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227555(US9340511, 4 | US9708269, 4f)
Affinity DataIC50:  1.40E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014350(CHEMBL323075 | Sodium; 3,5-dihydroxy-9,9-bis-(4-me...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014348(CHEMBL100188 | Sodium; 9,9-bis-(2,4-dimethyl-pheny...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM261512(2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carb...)
Affinity DataIC50:  2.10E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)
Affinity DataIC50:  2.10E+3nMpH: 7.4Assay Description:Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM50431015(CHEMBL2338329 | US10889546, FG-4592 | US9115085, C...)
Affinity DataIC50:  2.10E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227556(US9340511, 5 | US9708269, 5f)
Affinity DataIC50:  2.20E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227558(US9340511, 7 | US9708269, 7f)
Affinity DataIC50:  2.20E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227558(US9340511, 7 | US9708269, 7f)
Affinity DataIC50:  2.20E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227556(US9340511, 5 | US9708269, 5f)
Affinity DataIC50:  2.20E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227554(US9340511, 2 | US9708269, 2f)
Affinity DataIC50:  3.50E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227554(US9340511, 2 | US9708269, 2f)
Affinity DataIC50:  3.50E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014351(CHEMBL323373 | Sodium; 8-(2-tert-butyl-2H-tetrazol...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014351(CHEMBL323373 | Sodium; 8-(2-tert-butyl-2H-tetrazol...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227557(US9340511, 6 | US9708269, 6f)
Affinity DataIC50:  5.20E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227557(US9340511, 6 | US9708269, 6f)
Affinity DataIC50:  5.20E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421879(CHEMBL2304072)
Affinity DataIC50:  5.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227553(US9340511, 1 | US9708269, 1f)
Affinity DataIC50:  7.90E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1(Homo sapiens (Human))
Fibrogen

US Patent
LigandPNGBDBM227553(US9340511, 1 | US9708269, 1f)
Affinity DataIC50:  7.90E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014357(CHEMBL318256 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)
Affinity DataIC50:  7.90E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014360(CHEMBL322399 | Sodium; 8-cyano-9,9-bis-(4-fluoro-p...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014353(CHEMBL319739 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014352(CHEMBL102468 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014367(CHEMBL103792 | Sodium; 10,10-bis-(4-fluoro-phenyl)...)
Affinity DataIC50:  1.30E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014366(CHEMBL102484 | Sodium; 8-(2-ethyl-2H-tetrazol-5-yl...)
Affinity DataIC50:  2.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014347(CHEMBL321715 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed