Found 14 Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1' and Ligand = 'BDBM50431015' 
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human PHD2 using 2OG as substrate and Fe2 as co-factor assessed as hydroxylation incubated for 15 mins in presence of L-asc...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of HIF-PHD2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of PHD2 (unknown origin) incubated for 15 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of PHD2 (181 to 426 residue) (unknown origin) measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of PHD2 (unknown origin) measured by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibition of PHD2 (181 to 426 residues) (unknown origin) using FITC-HIF1alpha (556 to 574 residues) as substrate after 60 mins by fluorescence polar...More data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:Displacement of FITC-HIF-1alpha (556 to 574 residues) from PHD2 (181 to 426 residues) (unknown origin) after 60 mins by fluorescence polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:Inhibition of FITC-HIF1alpha (556 to 574 residues) binding to PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using FITC-HIF1-alpha (556 to 574 residues) as substrate after 60 mins by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 599nMAssay Description:The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMpH: 7.4Assay Description:Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMpH: 7.4Assay Description:Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide were obtained from commercial sources, e...More data for this Ligand-Target Pair
Affinity DataIC50: 5.74E+3nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using HIF1-alpha (556 to 574 residues) as substrate in presence of 2-OG preincubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 6.11E+3nMAssay Description:Inhibition of PHD2 in human Hep3B cells assessed as increase in EPO production measured after 24 hrs by ELISAMore data for this Ligand-Target Pair
