Compile Data Set for Download or QSAR
maximum 50k data
Found 856 with Last Name = 'tonukunuru' and Initial = 'g'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50454871(CHEMBL4209835)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM412734(N-(3-fluoropyridin-4-yl)-2-(6-methylpyridin-2-yl)-...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM412755(N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrr...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM412745(N-(3-fluoropyridin-4-yl)-2-(6-(trifluoromethyl)pyr...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM198665(US9221796, 2b)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM198694(US9221796, 23b)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM198728(US9221796, 46, P-4)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM198726(US9221796, 46, P-2)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50330324(CHEMBL4170867)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM198728(US9221796, 46, P-4)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to GluN2B receptor in human cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50330409(CHEMBL4168402)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50330410(CHEMBL4161899)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM198735(US9221796, 48, P-3)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406730(N-[4-({2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2...)
Affinity DataIC50:  0.190nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406730(N-[4-({2-[6-(difluoromethyl)pyridin-2-yl]pyrrolo[2...)
Affinity DataIC50:  0.190nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407012((3-{[({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-...)
Affinity DataIC50: <0.25nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407009(N-(4-{[5-(morpholin-4-ylmethyl)-2-(pyridin-2-yl)py...)
Affinity DataIC50:  0.25nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406793(N-{5-[(4,4-difluoropiperidin-1-yl)methyl]-2-(6-met...)
Affinity DataIC50:  0.25nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412768(N-(3-fluoropyridin-4-yl)-5-methyl-2-(6-methylpyrid...)
Affinity DataIC50:  0.25nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406951(1-({[2-(5-fluoropyridin-2-yl)-4-[(3-fluoropyridin-...)
Affinity DataIC50: <0.25nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412735(2-(6-(difluoromethyl)pyridin-2-yl)-N-(3-fluoropyri...)
Affinity DataIC50:  0.25nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412743(N-(3-fluoropyridin-4-yl)-2-(pyridin-2-yl)-7H-pyrro...)
Affinity DataIC50:  0.260nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406957(3-fluoro-N-(5-{[(1-methylcyclobutyl)amino]methyl}-...)
Affinity DataIC50:  0.270nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407043(2-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-({2-[6-(tri...)
Affinity DataIC50:  0.300nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407051(N-[4-({2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[...)
Affinity DataIC50:  0.370nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412766(N-(4-((2-(6-(difluoromethyl)pyridin-2-yl)-7H-pyrro...)
Affinity DataIC50:  0.370nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406787(3-chloro-N-[2-(6-fluoropyridin-2-yl)pyrrolo[2,1-f]...)
Affinity DataIC50:  0.390nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406741(N-[4-({5-[(4,4-difluoropiperidin-1-yl)methyl]-2-(p...)
Affinity DataIC50:  0.400nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407010(N-(5-{[(2H-1,3-benzodioxol-5-ylmethyl)amino]methyl...)
Affinity DataIC50:  0.400nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412738(2-(pyrrolidin-1-yl)-N-(4-((2-(6-(trifluoromethyl)p...)
Affinity DataIC50:  0.420nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406783(N-{2-[6-(difluoromethyl)-5-fluoropyridin-2-yl]pyrr...)
Affinity DataIC50:  0.460nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406991(3-[4-({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-...)
Affinity DataIC50:  0.470nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406968((3S)-1-({4-[(3-fluoropyridin-4-yl)amino]-2-(6-meth...)
Affinity DataIC50:  0.490nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406990(4-[({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-2-...)
Affinity DataIC50:  0.520nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412739(2-(4-methylpiperazin-1-yl)-N-(4-((2-(6-(trifluorom...)
Affinity DataIC50:  0.530nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM412745(N-(3-fluoropyridin-4-yl)-2-(6-(trifluoromethyl)pyr...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412745(N-(3-fluoropyridin-4-yl)-2-(6-(trifluoromethyl)pyr...)
Affinity DataIC50:  0.560nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407017(3-fluoro-N-[2-(pyridin-2-yl)-5-({[2-(pyridin-2-yl)...)
Affinity DataIC50:  0.580nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406959(1-({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-2-y...)
Affinity DataIC50:  0.580nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412773(N-methyl-N-{2-[6-(trifluoromethyl)pyridin-2-yl]-7H...)
Affinity DataIC50:  0.590nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406721(3-chloro-N-[2-(5-fluoropyridin-2-yl)pyrrolo[2,1-f]...)
Affinity DataIC50:  0.590nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406967((3S)-1-({2-[6-(difluoromethyl)pyridin-2-yl]-4-[(3-...)
Affinity DataIC50:  0.590nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM407046(2-[(2-hydroxy-2-methylpropyl)amino]-N-[4-({2-[6-(t...)
Affinity DataIC50:  0.600nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412775(3-chloro-N-{2-[6-(trifluoromethyl)pyridin-2-yl]-7H...)
Affinity DataIC50:  0.600nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412746(2-(5-fluoro-6-methylpyridin-2-yl)-N-(3-fluoropyrid...)
Affinity DataIC50:  0.600nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412747(2-(6-(difluoromethyl)pyridin-2-yl)-4-(1H-pyrrolo[3...)
Affinity DataIC50:  0.640nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412774(3-(trifluoromethyl)-N-{2-[6-(trifluoromethyl)pyrid...)
Affinity DataIC50:  0.640nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412755(N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrr...)
Affinity DataIC50:  0.670nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406956(1-{2-[({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin...)
Affinity DataIC50:  0.700nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Bristol-Myer Squibb

US Patent
LigandPNGBDBM412734(N-(3-fluoropyridin-4-yl)-2-(6-methylpyridin-2-yl)-...)
Affinity DataIC50:  0.700nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails US Patent
Displayed 1 to 50 (of 856 total ) | Next | Last >>
Jump to: