Found 333 with Last Name = 'tytgat' and Initial = 'j' 
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.98E+4nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 178nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 1(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human Kv1.1 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 305nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 2(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of human Kv1.2 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Modulation of human Nav1.4 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ku Leuven
Curated by ChEMBL
Ku Leuven
Curated by ChEMBL
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of human ERG expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Modulation of human Nav1.3 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 6(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Rattus norvegicus)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
