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Found 185 with Last Name = 'vaidya' and Initial = 'a'
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50356634(CHEMBL1914702)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50356635(CHEMBL1914708)
Affinity DataKi:  64nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50299972(CHEMBL585164 | Octanedioic Acid [4-(3-Azido-5-azid...)
Affinity DataKi:  740nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
Dr. Hari Singh Gour University

Curated by ChEMBL
LigandPNGBDBM50403048(CHEMBL2216805)
Affinity DataKi:  2.60E+4nMAssay Description:Displacement of [3H]QNB from M1 receptor in Wistar rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084713(CHEMBL331551 | N-[5-Amino-6-(6-hydroxy-1-pyridin-3...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060848(CHEMBL3394751)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060837(CHEMBL3394744)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084693(2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084712(CHEMBL115896 | N-{4-[(1-Allyl-6-hydroxy-1,2,3,4-te...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084699(2-Fluoro-N-{4-[(6-hydroxy-1-pyridin-3-ylmethyl-1,2...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060843(CHEMBL3394748)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060893(CHEMBL3394753)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084701(2-(4-Benzenesulfonylamino-piperidin-1-yl)-N-(6-flu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103722(CHEMBL3084802 | N-{4-[5-Amino-1-(3-trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Binding affinity of the compound towards human neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084698(CHEMBL265104 | N-{4-[(6-Methoxy-1-pyridin-3-ylmeth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084700(4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084707(4-[(2-Fluoro-benzenesulfonylamino)-methyl]-cyclohe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084704(2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084703(4-[(2-Fluoro-benzenesulfonylamino)-methyl]-cyclohe...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060844(CHEMBL3394749)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103712(CHEMBL430414 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Affinity DataIC50:  15nMAssay Description:Binding affinity of the compound towards human neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50356635(CHEMBL1914708)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060903(CHEMBL3394756)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084709(2-Fluoro-N-{4-[(6-fluoro-1-pyridin-3-ylmethyl-1,2,...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084694(CHEMBL118621 | N-{4-[(1-Allyl-6-fluoro-1,2,3,4-tet...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084692(2-Amino-6-(2-fluoro-benzenesulfonylamino)-hexanoic...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084695(2-Fluoro-N-{4-[(6-methoxy-1-pyridin-3-ylmethyl-1,2...)
Affinity DataIC50:  23nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060846(CHEMBL3394750)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084710(CHEMBL117632 | N-{4-[(6-Fluoro-1-pyridin-3-ylmethy...)
Affinity DataIC50:  27nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084706(2-(3-Benzenesulfonylamino-pyrrolidin-1-yl)-N-(6-fl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060836(CHEMBL3394743)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060842(CHEMBL3394747)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060904(CHEMBL3394742)
Affinity DataIC50:  34nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060838(CHEMBL3394745)
Affinity DataIC50:  36nMAssay Description:Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060897(CHEMBL3394754)
Affinity DataIC50:  37nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084705(4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060863(CHEMBL3394752)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50356634(CHEMBL1914702)
Affinity DataIC50:  45nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060841(CHEMBL3394746)
Affinity DataIC50:  47nMAssay Description:Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50232053(CHEMBL271741 | N-(4-amino-biphenyl-3-yl)-benzamide...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084697(CHEMBL118931 | N-[6-(6-Methoxy-1-pyridin-3-ylmethy...)
Affinity DataIC50:  53nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060863(CHEMBL3394752)
Affinity DataIC50:  57nMAssay Description:Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060836(CHEMBL3394743)
Affinity DataIC50:  61nMAssay Description:Displacement of [125I]-Tyr14-nociceptin from human ORL1 expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
West Chester University

Curated by ChEMBL
LigandPNGBDBM50060844(CHEMBL3394749)
Affinity DataIC50:  69nMAssay Description:Displacement of [3H]DAMGO from human Mu opioid receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50387965(CHEMBL2057824)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50084702(4-(Benzenesulfonylamino-methyl)-cyclohexanecarboxy...)
Affinity DataIC50:  75nMAssay Description:Inhibition of [125I]-PYY binding to recombinant NPY Y5 receptor on HEK-293 cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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