Affinity DataKi: 0.0794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:The compound was screened in vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 43.7nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -40.5kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:The compound's binding affinity against Alpha-2B adrenergic receptor from rat kidney homogenate in the presence of phentolamineChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:The compound's binding affinity against Dopamine receptor D2Checked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 272nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 278nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 300nM ΔG°: -36.6kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 343nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 459nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 472nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 520nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 600nM ΔG°: -34.9kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 601nMAssay Description:Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -34.5kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -34.5kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 709nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 830nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair