TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]IPT from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brainMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]citalopram from SERT in rat brainMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brainMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brainMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]IDAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 0.980nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.25nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.49nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.65nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.65nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]MADAM from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 1.92nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.06nMAssay Description:Displacement of [3H]citalopram from SERT in rat brainMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 2.20nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.23nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.75nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 2.91nMAssay Description:Displacement of [3H]paroxetine from SERT in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]BRL 43694 from human 5-HT3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal corticesMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]BRL 43694 from human 5-HT3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Tours
Curated by ChEMBL
University Of Tours
Curated by ChEMBL
Affinity DataKi: 4.15nMAssay Description:Displacement of [3H]paroxetine from SERTMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 4.60nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 4.61nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of [3H]-nisoxatine binding to norepinephrine transporter (NET) of rat cortical homogenatesMore data for this Ligand-Target Pair