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Found 639 with Last Name = 'viviani' and Initial = 'f'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499970(CHEMBL3741505)
Affinity DataIC50:  3nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499970(CHEMBL3741505)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178284(US9120812, 69)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM135582(US8846654, 111)
Affinity DataIC50:  6.70nMpH: 7.5Assay Description:The assay is carried out in 1.5 ml Eppendorf tubes comprising 40 mM of Tris-HCl (pH 7.5), 15 mM of MgCl2, 1 mM of EGTA, 0.5 mg/ml of bovine serum alb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499966(CHEMBL3739742)
Affinity DataIC50:  9nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499969(CHEMBL3741095)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178350(US9120812, 135)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178395(US9120812, 180)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380043(CHEMBL2012612)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499984(CHEMBL3741333)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178283(US9120812, 68)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178388(US9120812, 173)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178230(US9120812, 15)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178399(US9120812, 184)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499969(CHEMBL3741095)
Affinity DataIC50:  13nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178226(US9120812, 11)
Affinity DataIC50:  13nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178341(US9120812, 126)
Affinity DataIC50:  13nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178436(US9120812, 221)
Affinity DataIC50:  13nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM135578(US8846654, 16)
Affinity DataIC50:  15nMpH: 7.5Assay Description:The assay is carried out in 1.5 ml Eppendorf tubes comprising 40 mM of Tris-HCl (pH 7.5), 15 mM of MgCl2, 1 mM of EGTA, 0.5 mg/ml of bovine serum alb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178282(US9120812, 67)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178236(US9120812, 21)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM135584(US8846654, 294)
Affinity DataIC50:  15nMpH: 7.5Assay Description:By using for PDE8 an enzymatic assay equivalent to that described for PDE7. PDE7 Enzymatic Assay: The assay is carried out in 1.5 ml Eppendorf tube...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499978(CHEMBL3741569)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178446(US9120812, 231)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178281(US9120812, 66)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178342(US9120812, 127)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178340(US9120812, 125)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499984(CHEMBL3741333)
Affinity DataIC50:  17nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178227(US9120812, 12)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178222(US9120812, 7)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178422(US9120812, 207)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178374(US9120812, 159)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178267(US9120812, 52)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178218(US9120812, 3)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178383(US9120812, 168 | US9120812, 169)
Affinity DataIC50:  18nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380043(CHEMBL2012612)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178417(US9120812, 202)
Affinity DataIC50:  19nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178231(US9120812, 16)
Affinity DataIC50:  19nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178358(US9120812, 143)
Affinity DataIC50:  19nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178337(US9120812, 122)
Affinity DataIC50:  19nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178438(US9120812, 223)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178298(US9120812, 83)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178266(US9120812, 51)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178339(US9120812, 124)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178387(US9120812, 172)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178327(US9120812, 112)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178297(US9120812, 82)
Affinity DataIC50:  21nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178286(US9120812, 71)
Affinity DataIC50:  21nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM178245(US9120812, 30)
Affinity DataIC50:  21nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499966(CHEMBL3739742)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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