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Found 91 with Last Name = 'voelter' and Initial = 'w'
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299244(CHEMBL591428 | N1-((2S,3S)-4-(cyclopropylamino)-3-...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299239(CHEMBL572940 | N-(4-Fluorophenyl)-11-oxo-10,11-dih...)
Affinity DataKi:  211nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299243(3-(6-Fluoro-1H-benzo[d]imidazol-2-yl)-5H-dibenzo[b...)
Affinity DataKi:  244nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299241(3-(5-(4-Fluorophenyl)-1H-imidazol-2-yl)-5H dibenzo...)
Affinity DataKi:  293nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299238(CHEMBL578437 | Methyl 11-Oxo-N-(pyridin-4-yl)-10,1...)
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299242(3-(3H-Imidazo[4,5-c]pyridin-2-yl)-5H-dibenzo[b,e][...)
Affinity DataKi:  309nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299240(3-(5-(Pyridin-4-yl)-1H-imidazol-2-yl)-5H dibenzo[b...)
Affinity DataKi:  348nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448175(CHEMBL3120552)
Affinity DataKi:  8.60E+3nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448176(CHEMBL3120570)
Affinity DataKi:  1.17E+4nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448174(CHEMBL3120548)
Affinity DataKi:  1.21E+4nMAssay Description:Non-competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448177(CHEMBL1576403)
Affinity DataKi:  1.56E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448178(CHEMBL3120574)
Affinity DataKi:  1.57E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448179(CHEMBL1544729)
Affinity DataKi:  1.68E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448184(CHEMBL3120558)
Affinity DataKi:  1.81E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448182(CHEMBL3120560)
Affinity DataKi:  1.81E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448180(CHEMBL3120571)
Affinity DataKi:  1.85E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448185(CHEMBL3120566)
Affinity DataKi:  1.93E+4nMAssay Description:Mixed-type inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataKi:  2.00E+4nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259806(CHEMBL4100768)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259804(CHEMBL4075051)
Affinity DataIC50:  85nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259801(CHEMBL4092083)
Affinity DataIC50:  98nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259800(CHEMBL4062635)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259799(CHEMBL4078427)
Affinity DataIC50:  120nMAssay Description:Inhibition of BACE1 in human H4 cells expressing human APP K595N/M596L double mutant assessed as decrease in amyloid beta 42 and amyloid beta 40 leve...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259797(CHEMBL4074001)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259798(CHEMBL4095483)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259803(CHEMBL4093064)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259805(CHEMBL4065393)
Affinity DataIC50:  310nMAssay Description:Inhibition of BACE1 in human H4 cells expressing human APP K595N/M596L double mutant assessed as decrease in amyloid beta 42 and amyloid beta 40 leve...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50259802(CHEMBL4071284)
Affinity DataIC50:  660nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus infected insect cells using rhodamine-EVNLDAEFK peptide as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448175(CHEMBL3120552)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448176(CHEMBL3120570)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448178(CHEMBL3120574)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448198(CHEMBL3120549)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448200(CHEMBL3120572)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448177(CHEMBL1576403)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448174(CHEMBL3120548)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448179(CHEMBL1544729)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448184(CHEMBL3120558)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448181(CHEMBL3120561)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448180(CHEMBL3120571)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448182(CHEMBL3120560)
Affinity DataIC50:  2.03E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448185(CHEMBL3120566)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448183(CHEMBL3120559)
Affinity DataIC50:  2.22E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448197(CHEMBL1400695)
Affinity DataIC50:  2.27E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448196(CHEMBL1500153)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448192(CHEMBL1971338)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448205(CHEMBL3120564)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM50448194(CHEMBL3120551)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University Karachi

Curated by ChEMBL
LigandPNGBDBM65935(1-(3-chlorophenyl)-3-(3-pyridinyl)thiourea | 1-(3-...)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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