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Found 14 with Last Name = 'vuong' and Initial = 'a'
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049295(7-ethyl-7-hydroxy-14-(3-hydroxymethyl-1-pyridinium...)
Affinity DataIC50:  100nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049303(7-ethyl-7-hydroxy-14-pyrazin-1-ium-1-ylmethyl-(7S)...)
Affinity DataIC50:  140nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049304(7-ethyl-7-hydroxy-14-(1H-1-imidazolylmethyl)-(7S)-...)
Affinity DataIC50:  160nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049292(8-ethyl-8-hydroxy-15-pyrazin-1-ium-1-ylmethyl-(8S)...)
Affinity DataIC50:  180nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-I isolated from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049296(7-ethyl-7-hydroxy-14-pyridazin-1-ium-1-ylmethyl-(7...)
Affinity DataIC50:  190nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049294(8-ethyl-8-hydroxy-15-(1-pyridiniumylmethyl)-(8S)-2...)
Affinity DataIC50:  190nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-I isolated from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049298(7-ethyl-7-hydroxy-14-(1H-imidazol-3-ium-3-ylmethyl...)
Affinity DataIC50:  200nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-I isolated from calf thymusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049297(7-ethyl-7-hydroxy-14-(1-pyridiniumylmethyl)-(7S)-7...)
Affinity DataIC50:  210nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049299(7-ethyl-7-hydroxy-14-(3-methyl-1H-imidazol-3-ium-1...)
Affinity DataIC50:  220nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049293(8-ethyl-8-hydroxy-15-pyridazin-1-ium-1-ylmethyl-(8...)
Affinity DataIC50:  250nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049302(8-ethyl-8-hydroxy-15-(4-hydroxymethyl-1-pyridinium...)
Affinity DataIC50:  340nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049300(8-ethyl-8-hydroxy-15-(3-methyl-1H-imidazol-3-ium-1...)
Affinity DataIC50:  520nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50049301(8-ethyl-8-hydroxy-15-(3-hydroxymethyl-1-pyridinium...)
Affinity DataIC50:  600nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Glaxo Wellcome Research Institute

Curated by ChEMBL
LigandPNGBDBM50008935((20S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Average concentration of compound to cause 50% inhibition of topoisomerase-I isolated from calf thymusMore data for this Ligand-Target Pair