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Found 93 with Last Name = 'wångsell' and Initial = 'f'
TargetCathepsin B(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50221798(CHEMBL395154 | cyclopropanesulfonic acid [(Z)-(1R,...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50312541(((S)-1-[(S)-1-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of human liver cathepsin D after 20 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312539(CHEMBL1076905 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312537(CHEMBL1076901 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312538(CHEMBL1076902 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50157439(3-((2R,3S)-3-((S)-2-((S)-2-((S)-2-amino-3-(2H-tetr...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312540(CHEMBL1076906 | N-[(1S,2S,4S)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  10nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50312537(CHEMBL1076901 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human liver cathepsin D after 20 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50312539(CHEMBL1076905 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human liver cathepsin D after 20 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50312540(CHEMBL1076906 | N-[(1S,2S,4S)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver cathepsin D after 20 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574730((hydrochloride salt): 3-[4-(Piperidin-4-yl)phenyl]...)
Affinity DataIC50:  151nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312539(CHEMBL1076905 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human BACE1 in HEK293 cells stably co-transfected with mutant APP(swAPP751) assessed as Amyloid beta 1-40 level after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333404(3-(R)-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetraz...)
Affinity DataIC50:  190nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50312538(CHEMBL1076902 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human liver cathepsin D after 20 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574735((Hydrochloride Salt): 3-[4-(3-Aminopropylcarbamoyl...)
Affinity DataIC50:  263nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574732(US11459296, Example 40)
Affinity DataIC50:  264nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574737((Hydrochloride Salt): 3-(2-Amino-1,3-benzothiazol-...)
Affinity DataIC50:  314nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312540(CHEMBL1076906 | N-[(1S,2S,4S)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human BACE1 in HEK293 cells stably co-transfected with mutant APP(swAPP751) assessed as Amyloid beta 1-40 level after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333403(3-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333402(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  430nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333391(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  440nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574714(3-(4-Methanesulfonylphenyl)- 1-sulfamoyl-1H-pyrrol...)
Affinity DataIC50:  444nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574716(3-(Pyridin-3-yl)-1-sulfamoyl- 1H-pyrrole-2-carboxy...)
Affinity DataIC50:  448nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50297935(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((S)-1-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574713(3-(p-tolyl)-1-sulfamoyl-1H- pyrrole-2-carboxylic a...)
Affinity DataIC50:  479nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574744(3-(6-Aminopyridin-3-yl)-2- (1H-tetrazol-5-yl)-1H- ...)
Affinity DataIC50:  506nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574729(US11459296, Example 26)
Affinity DataIC50:  512nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574726(3-[4- (Cyclopropylsulfonylamino) phenyl]-1-sulfamo...)
Affinity DataIC50:  548nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574727(3-(6-Acetamido-3-pyridyl)-1- sulfamoyl-pyrrole-2- ...)
Affinity DataIC50:  608nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574734(US11459296, Example 47)
Affinity DataIC50:  656nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333406(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  680nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574721(US11459296, Example 18)
Affinity DataIC50:  725nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574712((Free Acid): 3-(6-Aminopyridin-3-yl)-1-sulfamoyl-1...)
Affinity DataIC50:  826nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574740(3-[1-(3-Aminopropanoyl)-4- piperidyl]-1-sulfamoyl-...)
Affinity DataIC50:  834nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333397(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  870nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312537(CHEMBL1076901 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human BACE1 in HEK293 cells stably co-transfected with mutant APP(swAPP751) assessed as Amyloid beta 1-40 level after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574731(US11459296, Example 36)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574743((free tetrazole): 3-(1-Methyl-1H-pyrazol-4-yl)-2-(...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312542(CHEMBL1076908 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574739((free acid): 3-[1-(2-Aminoacetyl)-4-piperidyl]-1-s...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574738((free acid): 3-(1-Acetylpiperidin-4-yl)-1-sulfamoy...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574717(3-(Pyridin-4-yl)-1-sulfamoyl- 1H-pyrrole-2-carboxy...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574728(US11459296, Example 25)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50333405(3-(S)-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetraz...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574722(3-(3-Fluorophenyl)-1- sulfamoyl-pyrrole-2- carboxy...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Infex Therapeutics

US Patent
LigandPNGBDBM574724(US11459296, Example 22)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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