TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Antagonistic activity of the compound against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Antagonistic activity of the compound against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg .More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 510nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Affinity of the compound for human PMN LTB-4 receptors.More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Concentration of the compound inhibiting 1 nM LTB4-induced aggregation in GP polymorphonuclear (PMN) leukocytes.More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Concentration of the compound inhibiting the binding of [3H]-LTB4 to human whole cell neutrophilsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Affinity of the compound for guinea pig PMN LTB-4 receptors.More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonistic activity of the compound against human polymorphonuclear (PMN) LTB4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration of compound against binding of Cysteinyl leukotriene D4 receptor from guinea pig lung using [3H]-LTD4More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cellsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMNMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for LTB4 receptor binding, obtained from radioligand binding assay using human intact neutrophils PMNMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Concentration of the compound inhibiting the binding of [3H]-LTB4 to human neutrophilsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: >300nMAssay Description:Compound was evaluated for Leukotriene B4 receptor binding, obtained from radioligand binding assay using guinea pig spleen cell membraneMore data for this Ligand-Target Pair