Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50013562
Substrate
n/a
Meas. Tech.
ChEBML_52211
Ki
2.5±n/a nM
Citation
 Huang, FC; Galemmo, RA; Johnson, WH; Poli, GB; Morrissette, MM; Mencel, JJ; Warus, JD; Campbell, HF; Nuss, GW; Carnathan, GW Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity. J Med Chem 33:1194-200 (1990) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50013562
Synonyms:
7-Chloro-2-{4-[2-(1H-tetrazol-5-ylmethyl)-benzyloxy]-phenoxymethyl}-quinoline | CHEMBL19158
Type:
Small organic molecule
Emp. Form.:
C25H20ClN5O2
Mol. Mass.:
457.912
SMILES:
Clc1ccc2ccc(COc3ccc(OCc4ccccc4Cc4nnn[nH]4)cc3)nc2c1
Structure:
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