Affinity DataKi: 0nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00200nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >0.00400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) of L-1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of horse liver alcohol dehydrogenase enzyme by Non-competitive inhibitionMore data for this Ligand-Target Pair
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Apparent inhibition constant against mammalian liver alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition constant against mammalian liver alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I isoform); Range is 33-37 nMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Inhibition constant against mammalian liver alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 890nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I)More data for this Ligand-Target Pair
TargetGlutamate dehydrogenase 1, mitochondrial(Bos taurus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition constant against mammalian glutamate dehydrogenase (GDH)More data for this Ligand-Target Pair
TargetGlutamate dehydrogenase 1, mitochondrial(Bos taurus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of bovine glutamate dehydrogenase (GDH) enzyme by competitive inhibitionMore data for this Ligand-Target Pair
TargetGlutamate dehydrogenase 1, mitochondrial(Bos taurus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Apparent inhibition constant against mammalian glutamate dehydrogenase (GDH)More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of horse liver alcohol dehydrogenase enzyme by non-competitive inhibitionMore data for this Ligand-Target Pair
TargetAlcohol dehydrogenase 1A(Homo sapiens (Human))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 2.10E+4nMAssay Description:Apparent inhibition constant against mammalian liver alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
TargetGlutamate dehydrogenase 1, mitochondrial(Bos taurus)
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 2.10E+4nMAssay Description:Inhibition constant against mammalian glutamate dehydrogenase (GDH)More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 1.88E+5nMAssay Description:Apparent inhibition constant against mammalian lactate dehydrogenase (LDH)More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 226nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Sloan-Kettering Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:In vitro 50% inhibition of topoisomerase II mediated k-DNA decatenationMore data for this Ligand-Target Pair