Compile Data Set for Download or QSAR
maximum 50k data
Found 330 with Last Name = 'watterson' and Initial = 'dm'
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255365((+/-)-cis-N1-((3S,4S)-4-((6-amino-4-methylpyridin-...)
Affinity DataKi:  14nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278675((+/-)-cis-6-((4-(2-(3-Fluorophenethylamino)-ethoxy...)
Affinity DataKi:  15nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278676((+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  53nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521018(US11149020, Compound 10 (MW-167))
Affinity DataKi:  86nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521021(US11149020, Compound 13 (MW-107))
Affinity DataKi:  91nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521019(US11149020, Compound 11 (MW-122))
Affinity DataKi:  98nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521025(US11149020, Compound 16 (MW-200))
Affinity DataKi:  100nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataKi:  100nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521045(US11149020, Compound 36 (MW-164))
Affinity DataKi:  101nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataKi:  101nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537599(CHEMBL4648060 | US11149020, Compound 2 (MW-108))
Affinity DataKi:  110nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537599(CHEMBL4648060 | US11149020, Compound 2 (MW-108))
Affinity DataKi:  114nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521017(US11149020, Compound 9 (MW-125))
Affinity DataKi:  127nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537598(CHEMBL4646628 | US11149020, Compound 1 (MW-181))
Affinity DataKi:  180nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase P236LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537598(CHEMBL4646628 | US11149020, Compound 1 (MW-181))
Affinity DataKi:  184nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521016(US11149020, Compound 7 (MW-077))
Affinity DataKi:  186nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521024(US11149020, Compound 15 (MW-156))
Affinity DataKi:  276nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537598(CHEMBL4646628 | US11149020, Compound 1 (MW-181))
Affinity DataKi:  320nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521047(N,N-dimethyl-5-(naphthalen-1-yl)-6-(pyridin-4-yl)p...)
Affinity DataKi:  343nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278744((+/-)-cis-6-((4-(2-(3-Fluorophenethoxy)ethylamino)...)
Affinity DataKi:  400nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataKi:  620nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537597(CHEMBL4645737 | US11149020, Compound 6 (MW-105))
Affinity DataKi:  657nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278745((+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255365((+/-)-cis-N1-((3S,4S)-4-((6-amino-4-methylpyridin-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278744((+/-)-cis-6-((4-(2-(3-Fluorophenethoxy)ethylamino)...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278746((+/-)-cis-N-(2-(4-((6-Amino-4-methylpyridin-2-yl)-...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278676((+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278675((+/-)-cis-6-((4-(2-(3-Fluorophenethylamino)-ethoxy...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278676((+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255365((+/-)-cis-N1-((3S,4S)-4-((6-amino-4-methylpyridin-...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278675((+/-)-cis-6-((4-(2-(3-Fluorophenethylamino)-ethoxy...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278744((+/-)-cis-6-((4-(2-(3-Fluorophenethoxy)ethylamino)...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278745((+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278746((+/-)-cis-N-(2-(4-((6-Amino-4-methylpyridin-2-yl)-...)
Affinity DataKi:  7.70E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278746((+/-)-cis-N-(2-(4-((6-Amino-4-methylpyridin-2-yl)-...)
Affinity DataKi:  1.07E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278745((+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50074653(CHEMBL385812 | R-K-K-Y-(Ach)-Y-R-R-K-NH2)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537594(CHEMBL4639028)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50074638(CHEMBL443574 | R-K-K-Y-K-Y-R-R-K-NH2)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537593(CHEMBL4639555 | US11149020, Compound 3 (MW-066))
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50074648(CHEMBL268790 | R-K-K-Y-(Ach)-(Ach)-R-R-K-NH2)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537606(CHEMBL4647072 | US11149020, Compound 34 (MW-154))
Affinity DataIC50:  112nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50074635(CHEMBL425624 | R-K-K-Y-K-P-R-R-K-NH2)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521035(US11149020, Compound 26 (MW-025))
Affinity DataIC50:  130nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537593(CHEMBL4639555 | US11149020, Compound 3 (MW-066))
Affinity DataIC50:  130nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM521022(US11149020, Compound 14 (MW-109))
Affinity DataIC50:  131nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50074657(CHEMBL267348 | R-K-K-Y-K-S-R-R-K-NH2)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM50537594(CHEMBL4639028)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50074644(CHEMBL409544 | R-K-K-Y-K-F-R-R-K-NH2)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against MLCK (smooth muscle myosin light chain kinase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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