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Found 24 with Last Name = 'westley' and Initial = 'jw'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292405(CHEMBL485054 | leucettamidine)
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292406(CHEMBL485053 | leucettamine B)
Affinity DataKi:  1.00E+5nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292398((E)-5-octadecen-7,9-diynoic acid | CHEMBL489540)
Affinity DataIC50:  500nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)
Affinity DataIC50:  750nMAssay Description:Binding affinity to LTB4 receptor in human U937 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292397((Z)-5-octadecen-7,9-diynoic acid | CHEMBL504781)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292402((E)-octadecan-9-ynoic acid | CHEMBL482803)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292396((Z)-7-octedecan-9-ynoic acid | CHEMBL482601)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292399(7,9-tetradecadiynoic acid | CHEMBL501307)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50042185(4,5-Bis-benzo[1,3]dioxol-5-ylmethyl-1-methyl-1H-im...)
Affinity DataIC50:  4.60E+3nMAssay Description:Antagonist activity at LTB4 receptor in fura-2 loaded human U937 cells assessed as inhibition of LTB4-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292404(3-(1,3 dodecadiynyl)-6-oxiranebutanoic acid | CHEM...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292400(7,9-octadecadiynoic acid | CHEMBL485858)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292401(9-octadecynoic acid | CHEMBL482804 | Delta(9)-octa...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478563(CHEMBL450380)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478568(CHEMBL478973)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292403(6-hydroxy-7,9-octadecadiynoic acid | CHEMBL448462)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478565(CHEMBL476874)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478566(CHEMBL478974)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478567(CHEMBL476873)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478564(CHEMBL449762)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292405(CHEMBL485054 | leucettamidine)
Affinity DataIC50:  1.56E+4nMAssay Description:Displacement of [3H]LTB4 from LTB4 receptor expressed in human U937 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed