Compile Data Set for Download or QSAR
maximum 50k data
Found 123 with Last Name = 'wetterholm' and Initial = 'a'
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataKi:  18nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataKi:  46nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataKi:  100nMAssay Description:Inhibition constant was determined against epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition constant was determined against epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23983(3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...)
Affinity DataKi:  4.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23986(3,4-dihydro-1H-2-benzothiopyran-3-one | isothiochr...)
Affinity DataKi:  4.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataKi:  4.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23983(3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...)
Affinity DataKi:  4.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23978((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...)
Affinity DataKi:  6.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23979((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataKi:  8.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23983(3-amino-N-hydroxy-1,2,3,4-tetrahydronaphthalene-2-...)
Affinity DataKi:  1.00E+4nM ΔG°:  -29.0kJ/molepH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046327(3-Amino-1,4-diphenyl-butan-2-one | CHEMBL70658)
Affinity DataKi:  1.40E+4nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046331(((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyrylamino)-...)
Affinity DataKi:  1.50E+4nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046331(((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyrylamino)-...)
Affinity DataKi:  1.50E+4nMAssay Description:Compound was tested for inhibitory activity against Leukotriene A4 hydrolase from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23980((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...)
Affinity DataKi:  3.00E+4nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50279808((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyric acid me...)
Affinity DataKi:  5.00E+4nMAssay Description:Compound was tested for inhibitory activity against Leukotriene A4 hydrolase from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50279808((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyric acid me...)
Affinity DataKi:  5.00E+4nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23979((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataKi:  5.50E+4nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23980((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...)
Affinity DataKi:  8.00E+4nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23990(3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...)
Affinity DataKi:  8.00E+4nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23978((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...)
Affinity DataKi:  1.10E+5nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23975((3Z)-3-(methoxyimino)-1,2,3,4-tetrahydronaphthalen...)
Affinity DataKi:  1.30E+5nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23977((3Z)-3-[(2-phenylethoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataKi:  2.60E+5nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  0.5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.60nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against Leukotriene A4 hydrolase from human leukocytesMore data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23973(3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...)
Affinity DataIC50:  500nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  500nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046326(2-(3-Amino-2-oxo-4-phenyl-butyrylamino)-4-methyl-p...)
Affinity DataIC50:  500nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046329(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50:  600nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046321(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50:  800nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046319(3-[2-Amino-3-(4-benzyloxy-phenyl)-propionyl]-benzo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  3.50E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against Leukotriene A4 hydrolase from human leukocytesMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046315(2-Amino-3-(4-benzyloxy-phenyl)-1-(4-trifluoromethy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046340(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046325((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046335(6-Amino-5-oxo-7-phenyl-heptanoic acid | CHEMBL3077...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046320(3-Amino-2-hydroxy-4-phenyl-butyric acid benzyl est...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046329(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046321(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046330(3-Amino-2-oxo-4-phenyl-butyric acid methyl ester |...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046329(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046337(3-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyrylamino...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23980((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23979((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23977((3Z)-3-[(2-phenylethoxy)imino]-1,2,3,4-tetrahydron...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046321(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 123 total ) | Next | Last >>
Jump to: