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Found 65 with Last Name = 'whiting' and Initial = 'a'
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423885(CHEMBL2312431)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423888(CHEMBL2312414)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423886(CHEMBL2312428)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423887(CHEMBL2312415)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388829(CHEMBL2062753)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423884(CHEMBL2312432)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446548(CHEMBL3110181)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388828(CHEMBL2062743)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055861(CHEMBL3329968)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446543(CHEMBL3110178)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446549(CHEMBL3110180)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446544(CHEMBL3110188)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318675(4-Chloro-2-{[2-(3-nitrophenyl)-1,3-dioxo-2,3-dihyd...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055860(CHEMBL3329967)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446540(CHEMBL3110184)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446542(CHEMBL3110179)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446546(CHEMBL3110183)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446551(CHEMBL3110174)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388827(CHEMBL2062731)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446547(CHEMBL3110182)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055859(CHEMBL3329966)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50055859(CHEMBL3329966)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318676(4-Chloro-2-{[2-(4-hydroxymethylphenyl)-1,3-dioxo-2...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055862(CHEMBL3329969)
Affinity DataIC50:  4.37E+4nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318675(4-Chloro-2-{[2-(3-nitrophenyl)-1,3-dioxo-2,3-dihyd...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318674(4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446553(CHEMBL3110161)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388830(CHEMBL2062756)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446541(CHEMBL3110185)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446545(CHEMBL3110186)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446550(CHEMBL3110177)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446552(CHEMBL3110162)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446555(CHEMBL3110160)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446556(CHEMBL3110158)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318677(4-Chloro-2-{[2-(4-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318674(4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50055863(CHEMBL2252571)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClathrin heavy chain 1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50446554(CHEMBL3110159)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50266767(2,2'-(3,6-dioxocyclohexa-1,4-diene-1,4-diyl)bis(az...)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50055861(CHEMBL3329968)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50055860(CHEMBL3329967)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318676(4-Chloro-2-{[2-(4-hydroxymethylphenyl)-1,3-dioxo-2...)
Affinity DataIC50:  6.90E+5nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Helwan University

Curated by ChEMBL
LigandPNGBDBM50460103(CHEMBL4226012)
Affinity DataEC50:  383nMAssay Description:Transactivation of GST-tagged RARgamma LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Helwan University

Curated by ChEMBL
LigandPNGBDBM50460100(CHEMBL4226854)
Affinity DataEC50:  847nMAssay Description:Transactivation of GST-tagged RARgamma LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Helwan University

Curated by ChEMBL
LigandPNGBDBM50460101(CHEMBL4226389)
Affinity DataEC50:  109nMAssay Description:Transactivation of GST-tagged RARgamma LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Helwan University

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  18nMAssay Description:Transactivation of GST-tagged RARbeta LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

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