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Found 3355 with Last Name = 'whitlock' and Initial = 'ga'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319819(1-(2-(3-fluoro-2-methoxyphenyl)-1-phenylethyl)pipe...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310652((S)-3-chloro-N-isobutyl-2-methyl-N-(pyrrolidin-3-y...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310647((S)-2,3-dichloro-N-phenyl-N-(pyrrolidin-3-yl)benza...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310662((S)-2,4-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310661((S)-2,3-dichloro-N-neopentyl-N-(pyrrolidin-3-yl)be...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188048((+)-1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazin...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188048((+)-1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazin...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310650((S)-3,4-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256615((R)-3-fluoro-1-((5-fluoro-1-(1H-imidazol-2-yl)-2,3...)
Affinity DataKi:  5nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50136680(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262626(CHEMBL515936 | Ethanesulfonic acid biphenyl-2-ylme...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262625(CHEMBL476312 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310649((S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310646((S)-2,3-dichloro-N-(2H-pyran-4-yl)-N-(pyrrolidin-3...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310644((S)-2,3-dichloro-N-cyclopentyl-N-(pyrrolidin-3-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310656((S)-2,3-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87043((R)-2-((R)-(4-fluoro-2-methoxyphenoxy)(phenyl)meth...)
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310656((S)-2,3-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262415((S)-N-(biphenyl-2-ylmethyl)-N-(pyrrolidin-3-yl)iso...)
Affinity DataKi:  6nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262627(CHEMBL476313 | Propane-1-sulfonic acid biphenyl-2-...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310666((S)-2-chloro-4-fluoro-N-isobutyl-N-(pyrrolidin-3-y...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262684(CHEMBL514232 | N-(1,1'-biphenyl-2-ylmethyl)-N',N'-...)
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319833(1-(2-(2,3-dihydrobenzofuran-7-yl)-1-phenylethyl)pi...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019696(CHEMBL3286557)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319823(1-(1-(3-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319824(1-(1-(4-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87036((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262678((S)-ethyl biphenyl-2-ylmethyl(pyrrolidin-3-yl)carb...)
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319831((R)-2-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | C...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87037((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(3-fluorophe...)
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262411((S)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319820(1-(2-(2-fluoro-6-methoxyphenyl)-1-phenylethyl)pipe...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319827(1-(2-(2-(difluoromethoxy)phenyl)-1-(4-fluorophenyl...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50262679(CHEMBL478835 | Propane-2-sulfonic acid biphenyl-2-...)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87027((R)-2-((R)-(2,3-difluorophenoxy)(phenyl)methyl)mor...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87025((R)-2-((R)-(2,3-dihydrobenzofuran-7-yloxy)(phenyl)...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87032((R)-2-((R)-(2-chloro-4-fluorophenoxy)(phenyl)methy...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87043((R)-2-((R)-(4-fluoro-2-methoxyphenoxy)(phenyl)meth...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319822(1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50310646((S)-2,3-dichloro-N-(2H-pyran-4-yl)-N-(pyrrolidin-3...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310653((S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-y...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87027((R)-2-((R)-(2,3-difluorophenoxy)(phenyl)methyl)mor...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM87024((R)-2-((R)-(4-fluoro-2-methylphenoxy)(phenyl)methy...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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